Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions

被引：0

作者：

Hajj-Boutros, Guy ^{[1
,2
]}

Faust, Andrea ^{[1
,2
,3
]}

Muscedere, John ^{[4
,5
]}

Kim, Perry ^{[4
]}

Abumrad, Naji ^{[6
]}

Chevalier, Stephanie ^{[7
]}

Aubertin-Leheudre, Mylene ^{[8
]}

Bergman, Howard ^{[3
,9
]}

Bowdish, Dawn ^{[10
]}

Burford, Jessica ^{[11
]}

Carrington-Lawrence, Stacy ^{[12
]}

Cote, Helene ^{[13
]}

Dawe, David E. ^{[14
,15
]}

Barreto, Philipe de Souto ^{[16
]}

Farrelly, Colin ^{[17
]}

Fowler, Robert ^{[18
]}

Gouspillou, Gilles ^{[8
]}

Harrington, Lea ^{[19
]}

Lautrup, Sofie ^{[20
,21
]}

Howlett, Susan ^{[22
]}

Imani, Mahdi ^{[23
,24
]}

Kirkland, James ^{[25
]}

Kuchel, George ^{[26
]}

Mallette, Frederick A. ^{[27
,28
]}

Morais, Jose A. ^{[1
,2
]}

Newman, John C. ^{[29
]}

Pullman, Daryl ^{[30
]}

Sierra, Felipe ^{[31
]}

Van Raamsdonk, Jeremy ^{[32
]}

Watt, Jennifer ^{[18
]}

Rylett, Rebecca Jane ^{[33
]}

Duque, Gustavo ^{[1
,2
,3
]}

机构：

[1] McGill Univ, Dept Med, Montreal, PQ, Canada

[2] McGill Univ, Res Inst, Hlth Ctr, Montreal, PQ, Canada

[3] Schouela Ctr Excellence Sustainable Hlth Sr Schoue, Montreal, PQ, Canada

[4] Canadian Frailty Network, Kingston, ON, Canada

[5] Queens Univ, Dept Crit Care Med, Kingston, ON, Canada

[6] Vanderbilt Univ, Med Ctr, Dept Surg, Div Surg Oncol & Endocrine Surg, Nashville, TN USA

[7] McGill Univ, Sch Human Nutr, Montreal, PQ, Canada

[8] Univ Quebec Montreal, Fac Sci, Dept Sci Act Phys, Montreal, PQ, Canada

[9] McGill Univ, Fac Med & Hlth Sci, Dept Family Med, Montreal, PQ, Canada

[10] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada

[11] Western Univ, Fac Hlth Sci, Arthur Labatt Family Sch Nursing, London, ON, Canada

[12] Natl Inst Aging, Div Aging Biol, NIH, Bethesda, MD USA

[13] Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC, Canada

[14] Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Internal Med, Winnipeg, MB, Canada

[15] Paul Albrechtsen Res Inst CancerCare Manitoba, Winnipeg, MB, Canada

[16] INSERM, UMR 1295, CERPOP, Toulouse, France

[17] Queens Univ, Dept Polit Studies, Kingston, ON, Canada

[18] Sunnybrook Hlth Sci Ctr, Dept Crit Care Med, Toronto, ON, Canada

[19] Univ Toronto, Dept Biochem, Toronto, ON, Canada

[20] Univ Oslo, Akershus Univ Hosp, Dept Clin Mol Biol EpiGen, Sykehusveien 25, N-1478 Lorenskog, Norway

[21] Akershus Univ Hosp, Lorenskog, Norway

[22] Dalhousie Univ, Dept Med Geriatr Med, Halifax, NS, Canada

[23] Univ Melbourne, Australian Inst Musculoskeletal Sci AIMSS, Gerosci & Osteosarcopenia Res Program, St Albans, Vic, Australia

[24] Western Hlth, St Albans, Vic, Australia

[25] Mayo Clin, Rochester, MN USA

[26] Univ Connecticut, UConn Ctr Aging, Sch Med, UConn Hlth, Farmington, CT USA

[27] Univ Montreal, Dept Med, Montreal, PQ, Canada

[28] Maisonneuve Rosemont Hosp, Res Ctr, Montreal, PQ, Canada

[29] Buck Inst Res Aging, Novato, CA USA

[30] Mem Univ, Fac Med, St John, NF, Canada

[31] Hevolut Fdn, Riyadh, Saudi Arabia

[32] McGill Univ Hlth Ctr, Res Inst, Montreal, PQ, Canada

[33] Western Univ, Dept Physiol & Pharmacol, London, ON, Canada

来源：

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2024年 / 79卷 / 07期

基金：

加拿大健康研究院;

关键词：

Aging; Animal studies; Clinical trials; Geroscience; Translational Research; CELLULAR SENESCENCE; OLDER-PEOPLE; PROTEIN; CARE; NUTRITION; DISEASE; MUSCLE; CANCER; NUAGE; MEN;

D O I：

10.1093/gerona/glae069

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.

引用

页数：9

共 50 条

[1] Navigating Breast Cancer Oligometastasis and Oligoprogression: Current Landscape and Future Directions
Yoon, Stephanie M.
Bazan, Jose G.
[J]. CURRENT ONCOLOGY REPORTS, 2024, 26 (06) : 647 - 664
[2] Navigating the Landscape of Hydrocortisone Administration in Septic Shock: Current Concepts and Future Directions
Kommareddy Jr, Anirudh
Vagha, Jayant D.
Meshram, Revat J.
[J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (12)
[3] The Practice of Clinical Forensic Psychology in Canada: Current Landscape and Future Directions
Goldenson, Julie
Nijdam-Jones, Alicia
Druhn, Nicholas
Hill, David
Coupland, Sarah
Roesch, Ronald
[J]. CANADIAN PSYCHOLOGY-PSYCHOLOGIE CANADIENNE, 2023, 64 (04): : 306 - 312
[4] Landscape Metrics: Past Progress and Future Directions
Amy E. Frazier
Peter Kedron
[J]. Current Landscape Ecology Reports, 2017, 2 (3) : 63 - 72
[5] Navigating the Landscape: A Comprehensive Review of Current Virus Databases
Ritsch, Muriel
Cassman, Noriko A.
Saghaei, Shahram
Marz, Manja
Wu, Nicholas C.
[J]. VIRUSES-BASEL, 2023, 15 (09):
[6] Ergonomics in Urology: Current Landscape and Future Directions
Kaldany, Alain
V. Patel, Hiren
Shaw, Nathan M.
Jones, Charles P.
Breyer, Benjamin N.
[J]. UROLOGY, 2024, 184 : 235 - 243
[7] Anticipatory nausea: current landscape and future directions
Ahrari, Soha
Chow, Ronald
Goodall, Shannon
DeAngelis, Carlo
[J]. ANNALS OF PALLIATIVE MEDICINE, 2017, 6 (01) : 1 - 2
[8] Current Challenges in Translational and Clinical fMRI and Future Directions
Specht, Karsten
[J]. FRONTIERS IN PSYCHIATRY, 2020, 10
[9] LYMPHOMAS - CURRENT PROGRESS AND FUTURE-DIRECTIONS
SAMUELS, BL
ULTMANN, JE
[J]. PERSPECTIVES IN BIOLOGY AND MEDICINE, 1989, 32 (04) : 513 - 525
[10] Leptin in humans: Current progress and future directions
Considine, RV
Caro, JF
[J]. CLINICAL CHEMISTRY, 1996, 42 (06) : 843 - 844

← 1 2 3 4 5 →