Genomic correlates of response and resistance to immune checkpoint inhibitors (ICI) in patients with metastatic urothelial carcinoma (mUC) in a real-world setting.

被引：0
|
作者：
Pramod, Nikhil
Makarov, Vladimir
Dawsey, Scott
Pavicic, Paul G.
Patgunarajah, Ubenthira
Nair, Monica
Ornstein, Moshe Chaim
Gilligan, Timothy D.
Wee, Christopher Eing
Nizam, Amanda
Mian, Omar Y.
Nguyen, Jane
Diaz-Montero, C. Marcela
Gupta, Shilpa
机构：
[1] Cleveland Clin, Lerner Coll Med, Cleveland, OH USA
[2] Cleveland Clin, Lerner Res Inst, Cleveland, OH USA
[3] Cleveland Clin, Cleveland, OH USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2024年 / 42卷 / 4_SUPPL期
关键词：
283-183-138-11076; 261-566-9718-9794; 3282-206-4957-326-5041; 3282-415; 3282-206-2798-3657; 283-183-138-226; 6; 5; 3; 2; 242; 1854; 1; 38092-27449; 38092-22447; 38092-34303; 38092-25802; 38092-25800; 38092-23141; 38092-20072; 38092-18225; 9;
D O I：
10.1200/JCO.2024.42.4_suppl.670
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：670 / 670
页数：1
相关论文
共 50 条
  • [21] Response to platinum-based therapy (PBT) and immune checkpoint inhibitors (ICI) in metastatic urothelial carcinoma (mUC) patients (pts) with genomic alterations (GA) in homologous recombination repair (HRR) genes
    Mendiratta, Prateek
    Loehr, Andrea
    Simmons, Andrew
    Barata, Pedro C.
    Klek, Stefan
    Pritchard, Amy
    Emamekhoo, Hamid
    Funchain, Pauline
    Sohal, Davendra
    Ali, Siraj Mahamed
    Gilligan, Timothy D.
    Ornstein, Moshe Chaim
    Garcia, Jorge A.
    Rini, Brian I.
    Grivas, Petros
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (06)
  • [22] Real-world experience and outcomes of immune-checkpoint inhibitors (ICI) in hepatocellular carcinoma (HCC)
    Paul, Samuel
    Min, Eric
    Benson, Katherine K.
    Xu, Menglin
    Noonan, Anne M.
    Mittra, Arjun
    Malalur, Pannaga G.
    Roychowdhury, Sameek
    Jin, Ning
    Hays, John L.
    Elkhatib, Rifat T.
    Rahman, Shafia
    Miller, Eric David
    Pardo, Dayssy Alexandra Diaz
    Manne, Ashish
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [23] REAL-WORLD OUTCOMES IN PATIENTS WITH PENILE SQUAMOUS CELL CARCINOMA (PSCC) RECEIVING IMMUNE CHECKPOINT INHIBITORS (ICI)
    Zhuang, Tony
    Goyal, Subir
    Brown, Jacqueline
    Carthon, Bradley
    Kucuk, Omer
    McClintock, Greta
    Yantorni, Lauren
    Bilen, Mehmet
    Master, Viraj
    Nazha, Bassel
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A498 - A499
  • [24] Decrease in derived neutrophil-to-lymphocyte ratio (dNLR) related to immune checkpoint inhibitors (ICI) benefit in patients with metastatic urothelial carcinoma (mUC)
    Oberoi, H. K.
    Ghiglione, L.
    Gorria Puga, T.
    Fernandez Manas, L.
    Ferrer Mileo, L.
    Orrillo Sarmiento, M.
    Prat, A.
    Reig Torras, O.
    Mellado, B.
    [J]. ANNALS OF ONCOLOGY, 2020, 31 : S596 - S597
  • [25] Effect of antibiotic, proton pump inhibitor, H2 blocker, metformin and statin use on outcomes with immune checkpoint inhibitors (ICIs) in patients (pts) with metastatic urothelial carcinoma (mUC) in a real-world setting
    Hobeika, Charbel
    Dawsey, Scott
    Patgunarajah, Ubenthira
    Lynn, David
    Pramod, Nikhil
    Wei, Wei
    Nair, Monica
    Maroli, Kimberly
    Martin, Allison
    Ornstein, Moshe Chaim
    Wee, Christopher Eing
    Gilligan, Timothy D.
    Nizam, Amanda
    Bonham, Amanda
    Mian, Omar Y.
    Pavicic, Paul G., Jr.
    Diaz-Montero, C. Marcela
    Gupta, Shilpa
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [26] Impact of pure versus mixed metastatic urothelial carcinoma (mUC) histology on response with immune checkpoint inhibitors (ICIs).
    Agarwal, Archana
    Nassar, Amin
    Pond, Gregory Russell
    Barletta, Justine A.
    Acosta, Andres
    Abou Alaiwi, Sarah
    Curran, Catherine
    Sonpavde, Guru
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (07)
  • [27] Association of biomarkers and outcomes in patients (pts) with metastatic urothelial carcinoma (mUC) treated with immune checkpoint inhibitors (ICIs).
    Reyes, Kevin R.
    Zhang, Li
    Zhu, Xiaolin
    Jindal, Tanya
    Deshmukh, Prianka
    de Kouchkovsky, Ivan
    Kumar, Vipul
    Maldonado, Edward
    Kwon, Daniel H.
    Chan, Emily
    Porten, Sima P.
    Borno, Hala
    Bose, Rohit
    Desai, Arpita
    Aggarwal, Rahul Raj
    Small, Eric Jay
    Fong, Lawrence
    Chou, Jonathan
    Friedlander, Terence W.
    Koshkin, Vadim S.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2023, 41
  • [28] Real-world impact of immune checkpoint inhibitors in metastatic uveal melanoma
    Bol, K. F.
    Ellebaek, E.
    Donia, M.
    Schmidt, H.
    Bastholt, L.
    Kiilgaard, J. F.
    Svane, I-M.
    [J]. ANNALS OF ONCOLOGY, 2019, 30 : 539 - 539
  • [29] Real-World Impact of Immune Checkpoint Inhibitors in Metastatic Uveal Melanoma
    Bol, Kalijn Fredrike
    Ellebaek, Eva
    Hoejberg, Lise
    Bagger, Mette Marie
    Larsen, Mathilde Skaarup
    Klausen, Tobias Wirenfeldt
    Kohler, Ulrich Heide
    Schmidt, Henrik
    Bastholt, Lars
    Kiilgaard, Jens Folke
    Donia, Marco
    Svane, Inge Marie
    [J]. CANCERS, 2019, 11 (10)
  • [30] Safety and Efficacy of Immune Checkpoint Inhibitors for Patients With Metastatic Urothelial Carcinoma and End-Stage Renal Disease: Experiences From Real-World Practice
    Kuo, Ming-Chun
    Su, Po-Jung
    Huang, Chun-Chieh
    Luo, Hao-Lun
    Chiu, Tai-Jan
    Li, Shau-Hsuan
    Wu, Chia-Che
    Liu, Ting-Ting
    Cheng, Yuan-Tso
    Kang, Chih-Hsiung
    Su, Yu-Li
    [J]. FRONTIERS IN ONCOLOGY, 2020, 10
12345