Safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses of AZD2373, an antisense oligonucleotide targeting APOL1

被引：0

作者：

Greasley, Peter J. ^{[1
]}

Agrawal, Nikhil ^{[2
]}

Althage, Magnus ^{[3
]}

Sanchez, Jose ^{[4
]}

Kirk, Sarah ^{[5
]}

Egeland, Erlend Johannessen ^{[6
]}

Astrand, Magnus ^{[6
]}

Westergren, Helena ^{[7
]}

Sherwood, James ^{[8
]}

Mccarthy, Michael ^{[9
]}

Patel, Uptal ^{[2
]}

Macphee, Iain ^{[10
]}

机构：

[1] BioPharmaceut R&D, Early Clin Dev, Cardiovasc Renal & Metab, Res & Early Dev, Gothenburg, Sweden

[2] BioPharmaceut R&D, Res & Early Dev, Cardiovasc Renal & Metab, Early Clin Dev, Gaithersburg, MD USA

[3] BioPharmaceut R&D, Translat Sci & Expt Med, Early Cardiovasc Renal & Metab, Gothenburg, Sweden

[4] AstraZeneca, Early Biometr Stat Innovat, Data Sci & Artificial Intelligence R&D, Gothenburg, Sweden

[5] AstraZeneca, Data Sci & Artificial Intelligence R&D, Early Biometr Stat Innovat, Cambridge, England

[6] AstraZeneca, Clin Pharmacol & Quantitat Pharmacol, Clin Pharmacol & Safety Sci R&D, Gothenburg, Sweden

[7] AstraZeneca, Precis Med & Biosamples Biopharmaceut, Precis Med & Biosamples Oncol R&D, Gothenburg, Sweden

[8] AstraZeneca, Precis Med & Biosamples Biopharmaceut, Precis Med & Biosamples Oncol R&D, Cambridge, England

[9] AstraZeneca, BioPharmaceut R&D, Cardiovasc Renal & Metab, Projects Res & Early Dev,Res & Early Dev, Gaithersburg, MD USA

[10] AstraZeneca, BioPharmaceut R&D, Early Clin Dev, Res & Early Dev,Cardiovasc Renal & Metab, Cambridge, England

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 2024年 / 39卷

关键词：

D O I：

暂无

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

1003

引用

页码：I1134 / I1135

页数：2

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