Recent Advancement of Nanotheranostics in Cancer Applications

被引:0
|
作者
Parveen, Suphiya [1 ]
Abira, R. [1 ]
Paikray, Safal Kumar [2 ]
Sahoo, Liza [2 ]
Tripathy, Nigam Sekhar [2 ]
Dilnawaz, Fahima [2 ]
机构
[1] Jain Deemed Univ, Sch Sci, Dept Biotechnol & Genet, Bengaluru 560027, Karnataka, India
[2] Centurion Univ Technol & Management, Sch Biotechnol, Jatni 752050, Orissa, India
关键词
Nanotheranostics; cancer drug delivery; imaging; QDs; upconversion nanoparticles; photosensitizer; UP-CONVERSION NANOPARTICLES; DRUG-DELIVERY SYSTEMS; MAGNETIC NANOPARTICLES; IN-VIVO; THERANOSTIC NANOPARTICLES; SILICA NANOPARTICLES; QUANTUM DOTS; PHOTOTHERMAL THERAPY; GOLD NANOPARTICLES; CONTRAST AGENTS;
D O I
10.2174/0115672018307617240514092110
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The field of nanomedicine shows promising implications in the concurrent delivery of therapeutic and diagnostic (theranostics) compounds in a single platform. Nanotheranostics is incredibly promising since it offers simultaneous non-invasive disease detection and treatment together with the exciting ability to track drug release and distribution in real-time, thereby forecasting and evaluating the efficacy of the therapy. The cancer theranostic approach improves the cancer prognosis safely and effectively. Common classes of nanoscale biomaterials, including magnetic nanoparticles, quantum dots, upconversion nanoparticles, mesoporous silica nanoparticles, carbon-based nanoparticles, and organic dye-based nanoparticles, have demonstrated enormous potential for theranostic activity. The need for improved disease detection and enhanced chemotherapeutic treatments, together with realistic considerations for clinically translatable nanomaterials will be key driving factors for theranostic agent research shortly. The developments of precision theranostic nanomaterials are employed in imaging systems like, MRI, PET, and SPECT with multifunctional ability. In this review, different nanoparticles/nanomaterials that are used/developed for theranostic activity are discussed.
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页数:19
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