Dynamics of Hepatitis B Virus Transmission with a Lévy Process and Vaccination Effects
被引:2
|
作者:
Shah, Sayed Murad Ali
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机构:
Northwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R ChinaNorthwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
Shah, Sayed Murad Ali
[1
]
Nie, Yufeng
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机构:
Northwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R ChinaNorthwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
Nie, Yufeng
[1
]
Din, Anwarud
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机构:
Sun Yat Sen Univ, Dept Math, Guangzhou 510275, Guangdong, Peoples R ChinaNorthwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
Din, Anwarud
[2
]
Alkhazzan, Abdulwasea
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机构:
Northwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
Sanaa Univ, Fac Sci, Dept Math, POB 1247, Sanaa, YemenNorthwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
Alkhazzan, Abdulwasea
[1
,3
]
机构:
[1] Northwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
[2] Sun Yat Sen Univ, Dept Math, Guangzhou 510275, Guangdong, Peoples R China
[3] Sanaa Univ, Fac Sci, Dept Math, POB 1247, Sanaa, Yemen
L & eacute;
vy jump;
stochastic HBV model;
white noise;
global solution;
extinction and persistence;
SIRS EPIDEMIC MODEL;
THRESHOLD;
BEHAVIOR;
D O I:
10.3390/math12111645
中图分类号:
O1 [数学];
学科分类号:
0701 ;
070101 ;
摘要:
This work proposes a novel stochastic model describing the propagation dynamics of the hepatitis B virus. The model takes into account numerous disease characteristics, and environmental disturbances were collected using L & eacute;vy jumps and the conventional Brownian motions. Initially, the deterministic model is developed, and the asymptotic behavior of the model's solution near the equilibria is examined. The deterministic model is transformed into a stochastic model while retaining the L & eacute;vy jumps and conventional Brownian motions. Under specific assumptions, the stochastic system is shown to have a unique solution. The study further investigates the conditions that ensure the extinction and persistence of the infection. The numerical solutions to both stochastic and deterministic systems were obtained using the well-known Milstein and RK4 techniques, and the analytical findings are theoretically confirmed. The simulation suggests that the noise intensities have a direct relationship with the amplitudes of the stochastic curves around the equilibria of the deterministic system. Smaller values of the intensities imply negligible fluctuations of trajectories around the equilibria and, hence, better describe the extinction and persistence of the infection. It has also been found that both Brownian motions and the L & eacute;vy jump had a significant influence on the oscillations of these curves. A discussion of the findings of the study reveals other important aspects as well as some future research guidelines. In short, this study proposes a novel stochastic model to describe the propagation dynamics of the hepatitis B virus.
机构:
Univ Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Ctr Invest Biomed Red Enfermedades Hepat & Digest, Gastrointestinal Unit, Madrid, SpainUniv Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Soleto, I.
Marin, A. C.
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机构:
Univ Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Ctr Invest Biomed Red Enfermedades Hepat & Digest, Gastrointestinal Unit, Madrid, SpainUniv Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Marin, A. C.
Mora, I.
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机构:
Univ Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Ctr Invest Biomed Red Enfermedades Hepat & Digest, Gastrointestinal Unit, Madrid, SpainUniv Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Mora, I.
Villagrasa, J. R.
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机构:
Hosp Univ La Princesa, Unidad Med Prevent, Madrid, SpainUniv Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Villagrasa, J. R.
Baldan-Martin, M.
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机构:
Univ Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Ctr Invest Biomed Red Enfermedades Hepat & Digest, Gastrointestinal Unit, Madrid, SpainUniv Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Baldan-Martin, M.
Ramirez, C.
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机构:
Univ Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
Ctr Invest Biomed Red Enfermedades Hepat & Digest, Gastrointestinal Unit, Madrid, SpainUniv Autonoma Madrid UAM, Hosp Univ La Princesa, Inst Invest Sanitaria Princesa IIS Princesa, Madrid, Spain
机构:
Qinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China
Cao, Li-Hua
Li, Yun-Ru
论文数: 0引用数: 0
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机构:
Capital Med Univ, Affiliated Beijing Ditan Hosp, Beijing 100000, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China
Li, Yun-Ru
Wang, Shou-Yun
论文数: 0引用数: 0
h-index: 0
机构:
Qinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China
Wang, Shou-Yun
Liu, Zhi-Min
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机构:
Qinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China
Liu, Zhi-Min
Sun, Shao-Chun
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机构:
Qinhuangdao Women & Childrens Hosp, Qinhuangdao 066000, Hebei, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China
Sun, Shao-Chun
Xu, Dong-Bo
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机构:
Qinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China
Xu, Dong-Bo
Zhang, Ji-Dong
论文数: 0引用数: 0
h-index: 0
机构:
Qinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R ChinaQinhuangdao Third Hosp, Liver Dis Ctr, Qinhuangdao 066001, Hebei, Peoples R China