Dynamics of Hepatitis B Virus Transmission with a Lévy Process and Vaccination Effects

被引:2
|
作者
Shah, Sayed Murad Ali [1 ]
Nie, Yufeng [1 ]
Din, Anwarud [2 ]
Alkhazzan, Abdulwasea [1 ,3 ]
机构
[1] Northwestern Polytech Univ, Sch Math & Stat, Xian 710072, Peoples R China
[2] Sun Yat Sen Univ, Dept Math, Guangzhou 510275, Guangdong, Peoples R China
[3] Sanaa Univ, Fac Sci, Dept Math, POB 1247, Sanaa, Yemen
关键词
L & eacute; vy jump; stochastic HBV model; white noise; global solution; extinction and persistence; SIRS EPIDEMIC MODEL; THRESHOLD; BEHAVIOR;
D O I
10.3390/math12111645
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
This work proposes a novel stochastic model describing the propagation dynamics of the hepatitis B virus. The model takes into account numerous disease characteristics, and environmental disturbances were collected using L & eacute;vy jumps and the conventional Brownian motions. Initially, the deterministic model is developed, and the asymptotic behavior of the model's solution near the equilibria is examined. The deterministic model is transformed into a stochastic model while retaining the L & eacute;vy jumps and conventional Brownian motions. Under specific assumptions, the stochastic system is shown to have a unique solution. The study further investigates the conditions that ensure the extinction and persistence of the infection. The numerical solutions to both stochastic and deterministic systems were obtained using the well-known Milstein and RK4 techniques, and the analytical findings are theoretically confirmed. The simulation suggests that the noise intensities have a direct relationship with the amplitudes of the stochastic curves around the equilibria of the deterministic system. Smaller values of the intensities imply negligible fluctuations of trajectories around the equilibria and, hence, better describe the extinction and persistence of the infection. It has also been found that both Brownian motions and the L & eacute;vy jump had a significant influence on the oscillations of these curves. A discussion of the findings of the study reveals other important aspects as well as some future research guidelines. In short, this study proposes a novel stochastic model to describe the propagation dynamics of the hepatitis B virus.
引用
收藏
页数:24
相关论文
共 50 条
  • [1] Mathematical Modeling of Transmission Dynamics and Optimal Control of Vaccination and Treatment for Hepatitis B Virus
    Kamyad, Ali Vahidian
    Akbari, Reza
    Heydari, Ali Akbar
    Heydari, Aghileh
    COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE, 2014, 2014
  • [2] Vaccination prevents perinatal transmission of hepatitis B virus
    Caroline Barranco
    Nature Clinical Practice Gastroenterology & Hepatology, 2006, 3 (5): : 243 - 243
  • [3] Selective Hepatitis B Virus Vaccination Has Reduced Hepatitis B Virus Transmission in The Netherlands
    Hahne, Susan
    van Houdt, Robin
    Koedijk, Femke
    van Ballegooijen, Marijn
    Cremer, Jeroen
    Bruisten, Sylvia
    Coutinho, Roel
    Boot, Hein
    PLOS ONE, 2013, 8 (07):
  • [4] Modeling the Effect of Vaccination and Treatment on the Transmission Dynamics of Hepatitis B Virus and HIV/AIDS Coinfection
    Endashaw, Engida Endriyas
    Mekonnen, Temesgen Tibebu
    JOURNAL OF APPLIED MATHEMATICS, 2022, 2022
  • [5] Understanding the dynamics of hepatitis B transmission: A stochastic model with vaccination and Ornstein-Uhlenbeck process
    Wu, Shuying
    Yuan, Sanling
    Lan, Guijie
    Zhang, Tonghua
    APPLIED MATHEMATICS AND COMPUTATION, 2024, 476
  • [6] Hepatitis B virus transmission pattern and vaccination efficiency in Uzbekistan
    Avazova, Dildora
    Kurbanov, Fuat
    Tanaka, Yasuhito
    Sugiyama, Masaya
    Radchenko, Ivan
    Ruziev, Dilmurod
    Musabaev, Erkin
    Mizokami, Masashi
    JOURNAL OF MEDICAL VIROLOGY, 2008, 80 (02) : 217 - 224
  • [7] Dynamical behavior of a hepatitis B virus transmission model with vaccination
    Pang, Jianhua
    Cui, Jing-an
    Zhou, Xueyong
    JOURNAL OF THEORETICAL BIOLOGY, 2010, 265 (04) : 572 - 578
  • [8] Impact of Universal Vaccination on Intrafamilial Transmission of Hepatitis B Virus
    Mu, Shu-Chi
    Wang, Gen-Ming
    Jow, Guey-Mei
    Chen, Bing-Fang
    JOURNAL OF MEDICAL VIROLOGY, 2011, 83 (05) : 783 - 790
  • [9] Perinatal transmission of hepatitis B virus infection and vaccination in China
    Yao, JL
    GUT, 1996, 38 : S37 - S38
  • [10] On the sexual transmission dynamics of hepatitis B virus in China
    Zou, Lan
    Ruan, Shigui
    Zhang, Weinian
    JOURNAL OF THEORETICAL BIOLOGY, 2015, 369 : 1 - 12