Synthesis and Characterization of N-Unsubstituted 2-and 3-Furanimines

被引：1

作者：

Kpoezoun, Amavi ^{[1
,2
]}

Gazzeh, Houda ^{[1
,3
]}

Baba, Gnon ^{[2
]}

Guillemin, Jean-Claude ^{[1
]}

机构：

[1] Univ Rennes, Ecole Natl Super Chim Rennes, CNRS, ISCR,UMR6226, F-35000 Rennes, France

[2] Univ Lome, Dept Chim, Lab Chim Organ & Subst Naturelles, 01 BP, Lome 1515, Togo

[3] Inst Sci Mol, Equipe Chim Mol & Mat C2M, Batiment A12,351 Cours Liberat, F-33405 Talence, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 15期

关键词：

PRIMARY AMINES; IMINES; TRANSIMINATION; AZIDES;

D O I：

10.1021/acs.joc.4c00914

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-unsubstituted 2-furanmethanimine and 3-furanmethanimine are the simplest derivatives of an imine family containing numerous drugs. They have been prepared in the gas phase by dehydrocyanation of the corresponding alpha-aminonitriles, characterized by IR and NMR spectroscopy at low temperature and used in transimination reactions. The kinetic stability of the furanaldimines lies between that of alkylated and arylated derivatives, demonstrating the role played by the substituent. The triethylborane complexes of the aldimines were synthesized by reacting the corresponding nitriles with superhydride.

引用

页码：11026 / 11030

页数：5

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