Evaluation of the Agreement Between a New Pyramid Wavefront Sensor Aberrometer and Scheiner-Smirnov Aberrometers

PURPOSE: To assess agreement between a new aberrometer (Osiris -T; CSO) employing pyramid wavefront sensor technique and Scheiner-Smirnov aberrometer (OPD-Scan III; Nidek) on measuring ocular, corneal, and internal aberrations in healthy participants. METHODS: The measurements were conducted three times consecutively by an experienced examiner. The total root mean square (RMS) aberrations, higher order aberration RMS, coma Z3 +/- 1, trefoil Z3 +/- 3, spherical aberration Z40 , and astigmatism II Z4 +/- 2 up to 7th order were exported in both 4and 6 -mm pupil zones. The parameters between the two devices were statistically compared using the paired t -test, and the differences assessed with Bland -Altman plots and 95% limits of agreement. RESULTS: This prospective study included 70 right eyes of 70 healthy participants with an average age of 25.94 +/- 6.59 years (range: 18 to 47 years). The mean difference in the two devices ranged from 0.01 pm for astigmatism II Z4 +/- 2 to 0.63 pm for total RMS in 4 mm and from 0.01 to 1.41 pm in 6 -mm pupil size. The Bland -Altman analysis of ocular, corneal, and internal aberrations indicated high agreement between the two devices and the maximum absolute values for 95% limits of agreement ranged from 0.03 to 1.06 pm for 4 -mm pupil diameters and 0.12 to 1.13 pm for 6 -mm pupil diameters. CONCLUSIONS: The newly developed pyramid wavefront sensor technique aberrometer demonstrated a high agreement with a Scheiner-Smirnov aberrometer when measuring ocular, corneal, and internal aberrations in healthy participants. Thus, the two aberrometers may be considered interchangeable for clinical applications.