Research gaps and priorities for quantitative microbial risk assessment (QMRA)

被引:0
|
作者
Hamilton, Kerry A. [1 ,2 ,37 ]
Harrison, Joanna Ciol [1 ,2 ]
Mitchell, Jade [3 ]
Weir, Mark [4 ,5 ]
Verhougstraete, Marc [6 ]
Haas, Charles N. [7 ]
Nejadhashemi, A. Pouyan [3 ]
Libarkin, Julie [8 ]
Aw, Tiong Gim [8 ]
Bibby, Kyle [9 ]
Bivins, Aaron [10 ]
Brown, Joe [11 ]
Dean, Kara [3 ]
Dunbar, Gwyneth [3 ]
Eisenberg, Joseph N. S. [12 ]
Emelko, Monica [13 ]
Gerrity, Daniel [14 ]
Gurian, Patrick L. [7 ]
Hartnett, Emma [15 ]
Jahne, Michael [16 ]
Jones, Rachael M. [17 ]
Julian, Timothy R. [18 ]
Li, Hongwan [3 ]
Li, Yanbin [19 ]
Gibson, Jacqueline MacDonald [20 ]
Medema, Gertjan [21 ,22 ]
Meschke, J. Scott [23 ]
Mraz, Alexis [24 ]
Murphy, Heather [25 ]
Oryang, David [26 ]
Owusu-Ansah, Emmanuel de-Graft Johnson [27 ]
Pasek, Emily [8 ]
Pradhan, Abani K. [28 ,29 ]
Razzolini, Maria Tereza Pepe [30 ]
Ryan, Michael O. [7 ]
Schoen, Mary [31 ]
Smeets, Patrick W. M. H. [21 ,22 ]
Soller, Jeffrey [31 ]
Solo-Gabriele, Helena [32 ]
Williams, Clinton [33 ]
Wilson, Amanda M. [34 ]
Zimmer-Faust, Amy [35 ]
Alja'fari, Jumana [36 ]
Rose, Joan B. [3 ]
机构
[1] Arizona State Univ, Biodesign Inst, Ctr Environm Hlth Engn, Tempe, AZ USA
[2] Arizona State Univ, Sch Sustainable Engn & Built Environm, Tempe, AZ USA
[3] Michigan State Univ, Dept Biosyst & Agr Engn, E Lansing, MI USA
[4] Ohio State Univ, Div Environm Hlth Sci, Columbus, OH USA
[5] Ohio State Univ, Sustainabil Inst, Columbus, OH USA
[6] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ USA
[7] Drexel Univ, Dept Civil Architectural & Environm Engn, Philadelphia, PA USA
[8] Michigan State Univ, Dept Earth & Environm Sci, E Lansing, MI USA
[9] Univ Notre Dame, Dept Civil & Environm Engn & Earth Sci, Notre Dame, IN USA
[10] Louisiana State Univ, Dept Civil & Environm Engn, Baton Rouge, LA USA
[11] Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Environm Sci & Engn, Chapel Hill, NC USA
[12] Univ Michigan, Dept Epidemiol, Sch Publ Hlth, Ann Arbor, MI USA
[13] Univ Waterloo, Dept Civil & Environm Engn, Waterloo, ON, Canada
[14] Southern Nevada Water Author, Appl Res & Dev Ctr, Las Vegas, NV USA
[15] Risk Sci Int, Ottawa, ON, Canada
[16] US EPA, Off Res & Dev, Cincinnati, OH USA
[17] Univ Calif Los Angeles, Fielding Sch Publ Hlth, Dept Environm Hlth Sci, Los Angeles, CA USA
[18] Swiss Fed Inst Aquat Sci & Technol, Eawag, Dubendorf, Switzerland
[19] Univ Arkansas, Dept Biol & Agr Engn, Fayetteville, AR USA
[20] North Carolina State Univ, Dept Civil Construct & Environm Engn, Raleigh, NC USA
[21] KWR Water Res Inst, Nieuwegein, Netherlands
[22] Delft Univ Technol, Delft, Netherlands
[23] Univ Washington, Sch Publ Hlth, Dept Environm & Occupat Hlth Sci, Seattle, WA USA
[24] Coll New Jersey, Sch Nursing Hlth & Exercise Sci, Dept Publ Hlth, Ewing, NJ USA
[25] Univ Guelph, Ontario Vet Coll, Dept Pathobiol, Guelph, ON, Canada
[26] US Dept Hlth & Human Serv DHHS, Food & Drug Adm FDA, Ctr Food Safety & Appl Nutr CFSAN, College Pk, MD USA
[27] Kwame Nkrumah Univ Sci & Technol, RWESCK LISA Coll Sci, Dept Stat & Actuarial Sci, Kumasi, Ghana
[28] Univ Maryland, Dept Nutr & Food Sci, College Pk, MD USA
[29] Univ Maryland, Ctr Food Safety & Secur Syst, College Pk, MD USA
[30] Univ Sao Paulo, Sch Publ Hlth, Sao Paulo, SP, Brazil
[31] Soller Environm, Berkeley, CA USA
[32] Univ Miami, Coll Engn, Dept Chem Environm & Mat Engn, Coral Gables, FL USA
[33] US Arid Land Agr Res Ctr, Maricopa, AZ USA
[34] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Community Environm & Policy Dept, Tucson, AZ USA
[35] Nature Conservancy, San Francisco, CA USA
[36] Natl Inst Stand & Technol NIST, Gaithersburg, MD USA
[37] Arizona State Univ, 1001 S McAllister Ave, Tempe, AZ 85281 USA
关键词
coronavirus disease 2019; environmental health; pathogens; quantitative microbial risk assessment; risk analysis; safety; DOSE-RESPONSE MODEL; MYCOBACTERIUM-AVIUM COMPLEX; PUBLIC-HEALTH; WATER-QUALITY; POTABLE REUSE; EXPOSURE; LEGIONELLA; REDUCTION; INFECTION; FRAMEWORK;
D O I
10.1111/risa.14318
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The coronavirus disease 2019 pandemic highlighted the need for more rapid and routine application of modeling approaches such as quantitative microbial risk assessment (QMRA) for protecting public health. QMRA is a transdisciplinary science dedicated to understanding, predicting, and mitigating infectious disease risks. To better equip QMRA researchers to inform policy and public health management, an Advances in Research for QMRA workshop was held to synthesize a path forward for QMRA research. We summarize insights from 41 QMRA researchers and experts to clarify the role of QMRA in risk analysis by (1) identifying key research needs, (2) highlighting emerging applications of QMRA; and (3) describing data needs and key scientific efforts to improve the science of QMRA. Key identified research priorities included using molecular tools in QMRA, advancing dose-response methodology, addressing needed exposure assessments, harmonizing environmental monitoring for QMRA, unifying a divide between disease transmission and QMRA models, calibrating and/or validating QMRA models, modeling co-exposures and mixtures, and standardizing practices for incorporating variability and uncertainty throughout the source-to-outcome continuum. Cross-cutting needs identified were to: develop a community of research and practice, integrate QMRA with other scientific approaches, increase QMRA translation and impacts, build communication strategies, and encourage sustainable funding mechanisms. Ultimately, a vision for advancing the science of QMRA is outlined for informing national to global health assessments, controls, and policies.
引用
收藏
页码:2521 / 2536
页数:16
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