Tumor NLRP3 inflammasome activity mediates resistance to Anti-PD-1 immunotherapy in advanced gastroesophageal cancer

被引:0
|
作者
Yarla, Nagendra
Howell, Kaylee
Y-Van Nguyen
Niedwiecki, Donna
Uronis, Hope
Strickler, John
DeVito, Nicholas C.
Theivanthiran, Bala
Hanks, Brent A.
机构
关键词
D O I
10.1158/1538-7445.AM2024-7521
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
7521
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Circular RNA circNCOA3 promotes tumor progression and anti-PD-1 resistance in colorectal cancer
    Chen, Dong-Liang
    Chen, Nuo
    Sheng, Hui
    Zhang, Dong-Sheng
    CANCER DRUG RESISTANCE, 2024, 7
  • [32] Modification of the Tumor Microenvironment Enhances Anti-PD-1 Immunotherapy in Metastatic Melanoma
    Shi, Guilan
    Scott, Megan
    Mangiamele, Cathryn G.
    Heller, Richard
    PHARMACEUTICS, 2022, 14 (11)
  • [33] Tumor Immunologic Heterogeneity Influences Response to Radiation and Anti-PD-1 Immunotherapy
    Aguilera, T. A.
    Rafat, M.
    Kariolis, M. S.
    Graves, E. E.
    Giaccia, A. J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2015, 93 (03): : S211 - S211
  • [34] Enhanced Activity of NLRP3 Inflammasome in the Lung of Patients with Anti-Synthetase Syndrome
    Ramos-Martinez, Espiridion
    Vega-Sanchez, Angel E.
    Perez-Rubio, Gloria
    Mejia, Mayra
    Buendia-Roldan, Ivette
    Gonzalez-Perez, Montserrat, I
    Mateos-Toledo, Heidegger N.
    Andrade, Warrison A.
    Falfan-Valencia, Ramces
    Rojas-Serrano, Jorge
    CELLS, 2023, 12 (01)
  • [35] Is anti-PD-1/PD-L1 immunotherapy sensitizing for conventional cancer therapies?
    Matias, M.
    Aspeslagh, S.
    Palomar, V.
    Lanoy, E.
    Dercle, L.
    Even, C.
    Ferte, C.
    Hollebecque, A.
    Marabelle, A.
    Massard, C.
    Soria, J-C.
    Postel-Vinay, S.
    ANNALS OF ONCOLOGY, 2016, 27
  • [36] Computational modeling analysis of the tumor response to anti-PD-1 immunotherapy.
    Valentinuzzi, Damijan
    Ursic, Katja
    Simoncic, Urban
    Maruna, Matea
    Turk, Marusa
    Vrankar, Martina
    Cemazar, Maja
    Sersa, Gregor
    Jeraj, Robert
    CANCER IMMUNOLOGY RESEARCH, 2020, 8 (04) : 42 - 43
  • [37] Is anti-PD-1 immunotherapy a means for post-irradiation tumor clearance in head and neck cancer?
    Koukourakis, Ioannis M.
    Papadimitriou, Marios
    Desse, Dimitra
    Zygogianni, Anna
    Papadimitriou, Christos
    Koukourakis, Michael, I
    MEDICAL ONCOLOGY, 2022, 39 (12)
  • [38] Is anti-PD-1 immunotherapy a means for post-irradiation tumor clearance in head and neck cancer?
    Ioannis M. Koukourakis
    Marios Papadimitriou
    Dimitra Desse
    Anna Zygogianni
    Christos Papadimitriou
    Michael I. Koukourakis
    Medical Oncology, 39
  • [39] Igniting hope: Harnessing NLRP3 inflammasome-GSDMD-mediated pyroptosis for cancer immunotherapy
    Li, Ling-Rui
    Chen, Lei
    Sun, Zhi-Jun
    LIFE SCIENCES, 2024, 354
  • [40] Mechanisms of resistance to anti-PD-1 immunotherapy through interferon pathway mutations
    Zaretsky, Jesse
    Garcia-Diaz, Angel
    Shin, Daniel S.
    Escuin-Ordinas, Helena
    Hugo, Willy
    Hu-Lieskovan, Siwen
    Eroglu, Zeynep
    Torrejon, Davis Y.
    Tumeh, Paul C.
    Lo, Roger S.
    Ribas, Antoni
    CANCER RESEARCH, 2017, 77