Pediatric lymphoproliferative disorders associated with inborn errors of immunity

被引:2
|
作者
Cheng, Jinjun [1 ,2 ,3 ,4 ]
Saldana, Blachy J. Davila [2 ,3 ,4 ,5 ]
Chandrakasan, Shanmuganathan [6 ]
Keller, Michael [2 ,3 ,4 ]
机构
[1] Childrens Natl Hosp, Dept Pathol & Lab Med, Washington, DC USA
[2] Childrens Natl Hosp, Ctr Canc & Blood Disorders, Washington, DC USA
[3] Childrens Natl Hosp, Ctr Canc, Washington, DC USA
[4] Childrens Natl Hosp, Immunol Res, Washington, DC USA
[5] George Washington Univ, Sch Med & Hlth Sci, Washington, DC USA
[6] Childrens Healthcare Atlanta, Aflac Canc & Blood Disorders Ctr, Atlanta, GA USA
关键词
Inborn errors of immunity; Lymphoproliferative disorder; Lymphoma; EBV; WHO classification; International consensus classification; CELL TRANSPLANTATION; LYMPHOMA; DISEASE; MUTATIONS; DEFICIENCY; LUNG; LYMPHADENOPATHY; CLASSIFICATION; HYPERPLASIA; PHENOTYPE;
D O I
10.1016/j.clim.2024.110332
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Both non-malignant and malignant lymphoproliferative disorders (LPD) are commonly seen in patients with inborn errors of immunity (IEI), which may be the presenting manifestations or may develop during the IEI disease course. Here we review the clinical, histopathological, and molecular features of benign and malignant LPD associated with IEI and recognize the diagnostic challenges.
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页数:9
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