Adjuvant Chemotherapy for Breast Cancer in Older Adult Patients
被引:0
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作者:
Gao, Ying
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机构:
Tianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R China
Tianjin Med Univ Canc Hosp, Natl Canc Clin Res Ctr, Tianjin Canc Clin Res Ctr, Dept Thyroid & Neck Canc, Tianjin 300060, Peoples R ChinaTianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R China
Gao, Ying
[1
,2
]
Hao, Jie
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机构:
Tianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R ChinaTianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R China
Hao, Jie
[1
]
Zhang, Zhendong
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机构:
Tianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R ChinaTianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R China
Zhang, Zhendong
[1
]
机构:
[1] Tianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R China
[2] Tianjin Med Univ Canc Hosp, Natl Canc Clin Res Ctr, Tianjin Canc Clin Res Ctr, Dept Thyroid & Neck Canc, Tianjin 300060, Peoples R China
breast cancer;
older adult patients;
chemotherapy;
assessment;
INTERNATIONAL SOCIETY;
UPDATED RECOMMENDATIONS;
EUROPEAN-SOCIETY;
WOMEN;
MANAGEMENT;
MORTALITY;
VALIDATION;
TRIAL;
INDEX;
D O I:
10.2147/CIA.S470262
中图分类号:
R592 [老年病学];
C [社会科学总论];
学科分类号:
03 ;
0303 ;
100203 ;
摘要:
Decision-making regarding adjuvant chemotherapy for older adults with breast cancer is a challenge because older adult patients often have poor physical health, frailty, and age-related comorbidities, which can compromise treatment outcome. Due to these considerations, doctors tend to use less chemotherapy for breast cancer in older adults. However, older patients in good general health could still benefit from chemotherapy. Careful benefit-risk assessment is essential to provide best care for each older adult patient. Due to a rapidly aging population, breast cancer in older adults is becoming a serious public health issue in China. In this mini review, we discuss the need, means, and tools to assess the benefits and risks of adjuvant chemotherapy in older adults with breast cancer. The contents of this review may drive decision-making with regard to the use and selection of adjuvant chemotherapy for older adult patients in China who are fit for the treatment.
机构:
St Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USASt Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USA
Hwang, Mark
Farasatpour, Mishel
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St Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USASt Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USA
Farasatpour, Mishel
Williams, Campbell D.
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St Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USASt Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USA
Williams, Campbell D.
Margenthaler, Julie A.
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Virgo, Katherine S.
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Amer Canc Soc, Atlanta, GA 30303 USASt Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USA
Virgo, Katherine S.
Johnson, Frank E.
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机构:
St Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USA
St Louis Vet Affairs Med Ctr, St Louis, MO 63106 USASt Louis Univ Hosp, Dept Surg, St Louis, MO 63110 USA
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Univ Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, EnglandUniv Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, England
Richards, Paul
Ward, Sue
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机构:
Univ Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, EnglandUniv Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, England
Ward, Sue
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机构:
Morgan, Jenna
Francis, Matthew
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h-index: 0
机构:
Publ Hlth England, Knowledge & Intelligence Team West Midlands, Birmingham, W Midlands, EnglandUniv Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, England
Francis, Matthew
Lawrence, Gill
论文数: 0引用数: 0
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机构:
Publ Hlth England, Knowledge & Intelligence Team West Midlands, Birmingham, W Midlands, EnglandUniv Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, England
Lawrence, Gill
Wyld, Lynda
论文数: 0引用数: 0
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机构:
Univ Sheffield, Acad Unit Surg Oncol, Sheffield S10 2TN, S Yorkshire, EnglandUniv Sheffield, Sch Hlth & Related Res, Sheffield S10 2TN, S Yorkshire, England
机构:
Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USA
Srokowski, Tomasz P.
Fang, Shenying
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USA
Fang, Shenying
Hortobagyi, Gabriel N.
论文数: 0引用数: 0
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机构:
Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USA
Hortobagyi, Gabriel N.
Giordano, Sharon H.
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机构:
Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77030 USA