Adjuvant Chemotherapy for Breast Cancer in Older Adult Patients

被引:0
|
作者
Gao, Ying [1 ,2 ]
Hao, Jie [1 ]
Zhang, Zhendong [1 ]
机构
[1] Tianjin Union Med Ctr, Dept Breast & Thyroid Surg, Tianjin 300121, Peoples R China
[2] Tianjin Med Univ Canc Hosp, Natl Canc Clin Res Ctr, Tianjin Canc Clin Res Ctr, Dept Thyroid & Neck Canc, Tianjin 300060, Peoples R China
关键词
breast cancer; older adult patients; chemotherapy; assessment; INTERNATIONAL SOCIETY; UPDATED RECOMMENDATIONS; EUROPEAN-SOCIETY; WOMEN; MANAGEMENT; MORTALITY; VALIDATION; TRIAL; INDEX;
D O I
10.2147/CIA.S470262
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Decision-making regarding adjuvant chemotherapy for older adults with breast cancer is a challenge because older adult patients often have poor physical health, frailty, and age-related comorbidities, which can compromise treatment outcome. Due to these considerations, doctors tend to use less chemotherapy for breast cancer in older adults. However, older patients in good general health could still benefit from chemotherapy. Careful benefit-risk assessment is essential to provide best care for each older adult patient. Due to a rapidly aging population, breast cancer in older adults is becoming a serious public health issue in China. In this mini review, we discuss the need, means, and tools to assess the benefits and risks of adjuvant chemotherapy in older adults with breast cancer. The contents of this review may drive decision-making with regard to the use and selection of adjuvant chemotherapy for older adult patients in China who are fit for the treatment.
引用
收藏
页码:1281 / 1286
页数:6
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