The article focuses on innovation as an organizational will to power inferred by Nietzsche as the desire to live, to manifest emotions, the feeling of life, the impulse of will and the power to realize and achieve what is desired. Based on the methodological approach used, it focuses on the bibliographic documentary review, with observation being the data collection technique. For Nietzsche, what is truly primordial about humanity is the intrinsic determination of the will, which in turn is the result that emanates from the movement of the position of values. This will has to do with the creative nature of values, which undoubtedly tells us about their existence. In a sense of conservation and increase of human life. In the same way, it is important to highlight McForland in terms of leadership where he defines it as the ability to influence others through integrity and thus create trust with his followers by affirming honesty and ethics as columns of that trust. Uniting these concepts with organizational innovation is finding new organizational designs by altering the internal structures of the organization and also implies changing the limits between the organization and the market under the figure of leadership, which, using the influence that it characterizes, would supervise and control. Redirect the personnel required by the organization in order to achieve and achieve correct management of innovation between the different departments and processes within it associated with the organizational will to power