This study investigates the dynamics between perceived cultural distance (PCD), cultural intelligence (CQ), and international students' sociocultural, psychological, and academic adjustment. It examines whether CQ (its total score and four sub-components separately from the total CQ) moderates the relationship between PCD and adjustment. By investigating all three dimensions of students' adjustment, and also distinguishing the four aspects of the CQ, it provides an especially fine-grained analysis of the link between PCD, CQ and international students' adjustment. In a cross-sectional study, 341 international college students from several universities in the Netherlands participated in an online survey. Moderation analysis (Hayes Process Macro) indicated that overall CQ and motivational CQ moderated only the relationship between PCD and sociocultural adjustment. Further analysis show that when age, gender, level of study, and region of origin controlled, PCD consistently predicted all aspects of students' adjustment negatively. Overall CQ predicted only sociocultural and academic adjusment, but motivational CQ influenced all aspects of adjustment. Together, these results provide an insightful understanding of the role of international students' CQ in their adjustment in the face of cultural differences.