共 50 条
- [21] Strong synergy with APR-246 and DNA-damaging drugs in primary cancer cells from patients with TP53 mutant High-Grade Serous ovarian cancerJournal of Ovarian Research, 9Åsa Fransson论文数: 0 引用数: 0 h-index: 0机构: Aprea AB,Karolinska Institutet Dept. of OncologyDaria Glaessgen论文数: 0 引用数: 0 h-index: 0机构: Aprea AB,Karolinska Institutet Dept. of OncologyJessica Alfredsson论文数: 0 引用数: 0 h-index: 0机构: Aprea AB,Karolinska Institutet Dept. of OncologyKlas G. Wiman论文数: 0 引用数: 0 h-index: 0机构: Aprea AB,Karolinska Institutet Dept. of OncologySvetlana Bajalica-Lagercrantz论文数: 0 引用数: 0 h-index: 0机构: Aprea AB,Karolinska Institutet Dept. of OncologyNina Mohell论文数: 0 引用数: 0 h-index: 0机构: Aprea AB,Karolinska Institutet Dept. of Oncology
- [22] APR-246 INDUCES AN INCREASE IN TUMOR IMMUNOGENICITY IN A P53 INDEPENDENT MANNERJOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A941 - A941Venkatesh, Divya论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAMichels, Judith论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USALu, Cailin论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USABudhu, Sadna论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAGeorge, Mariam论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAOuerfelli, Ouathek论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAAbrahmsen, Lars论文数: 0 引用数: 0 h-index: 0机构: Aprea Therapeut, Solna, Sweden Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAZappasodi, Roberta论文数: 0 引用数: 0 h-index: 0机构: MSKCC & Weil Cornell Med WCM, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAWolchok, Jedd论文数: 0 引用数: 0 h-index: 0机构: MSKCC & Weil Cornell Med WCM, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USAMerghoub, Taha论文数: 0 引用数: 0 h-index: 0机构: MSKCC & Weil Cornell Med WCM, New York, NY USA Mem Sloan Kettering Canc Ctr MSKCC, New York, NY USA
- [23] Strong synergy with APR-246 and DNA-damaging drugs in primary cancer cells from patients with TP53 mutant High-Grade Serous ovarian cancerJOURNAL OF OVARIAN RESEARCH, 2016, 9Fransson, Asa论文数: 0 引用数: 0 h-index: 0机构: Aprea AB, Solna, Sweden Aprea AB, Solna, SwedenGlaessgen, Daria论文数: 0 引用数: 0 h-index: 0机构: Karolinska Univ Hosp, Stockholm, Sweden Aprea AB, Solna, SwedenAlfredsson, Jessica论文数: 0 引用数: 0 h-index: 0机构: Aprea AB, Solna, Sweden Aprea AB, Solna, SwedenWiman, Klas G.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, CCK, Dept Oncol Pathol, Stockholm, Sweden Aprea AB, Solna, SwedenBajalica-Lagercrantz, Svetlana论文数: 0 引用数: 0 h-index: 0机构: Karolinska Univ Hosp, Stockholm, Sweden Karolinska Inst, CCK, Dept Oncol Pathol, Stockholm, Sweden Aprea AB, Solna, SwedenMohell, Nina论文数: 0 引用数: 0 h-index: 0机构: Aprea AB, Solna, Sweden Aprea AB, Solna, Sweden
- [24] APR-246 reactivates mutant p53 by targeting cysteines 124 and 277Cell Death & Disease, 9Qiang Zhang论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)Vladimir J. N. Bykov论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)Klas G. Wiman论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)Joanna Zawacka-Pankau论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)
- [25] APR-246 reactivates mutant p53 by targeting cysteines 124 and 277CELL DEATH & DISEASE, 2018, 9Zhang, Qiang论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, Sweden Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, SwedenBykov, Vladimir J. N.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, Sweden Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, SwedenWiman, Klas G.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, Sweden Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, SwedenZawacka-Pankau, Joanna论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Microbiol Tumor & Cell Biol MTC, SE-17177 Stockholm, Sweden Karolinska Inst, CCK, Dept Oncol & Pathol, SE-17176 Stockholm, Sweden
- [26] APR-246 Combined with Azacitidine (AZA) in TP53 Mutated Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). a Phase 2 Study By the Groupe Francophone Des Myelodysplasies (GFM)BLOOD, 2019, 134Cluzeau, Thomas论文数: 0 引用数: 0 h-index: 0机构: Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, France Cote DAzur Univ, Mediterranean Ctr Mol Med, INSERM, U1065, Nice, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceSebert, Marie论文数: 0 引用数: 0 h-index: 0机构: Hop St Louis, Hematol Clin, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceRahme, Ramy论文数: 0 引用数: 0 h-index: 0机构: Hop St Louis, Hematol Clin, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceCuzzubbo, Stefania论文数: 0 引用数: 0 h-index: 0机构: Hosp St Louis, Dept Neurol, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceWalter-petrich, Anouk论文数: 0 引用数: 0 h-index: 0机构: Hosp St Louis, SBIM, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceChe, Jacqueline Lehmann论文数: 0 引用数: 0 h-index: 0机构: Hosp St Louis, Dept Pharm, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FrancePeterlin, Pierre论文数: 0 引用数: 0 h-index: 0机构: Hop Hotel Dieu & Hme, Clin Hematol, Nantes 1, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceBeve, Blandine论文数: 0 引用数: 0 h-index: 0机构: French Grp Myelodysplasia, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceAttalah, Habiba论文数: 0 引用数: 0 h-index: 0机构: French Grp Myelodysplasia, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceChermat, Fatiha论文数: 0 引用数: 0 h-index: 0机构: Grp Francophone Myelodysplasies, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceMiekoutima, Elsa论文数: 0 引用数: 0 h-index: 0机构: Hosp St Louis, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceBeyne-Rauzy, Odile论文数: 0 引用数: 0 h-index: 0机构: IUCT, Toulouse, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceRecher, Christian论文数: 0 引用数: 0 h-index: 0机构: TBD, Toulouse, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceStamatoullas, Aspasia论文数: 0 引用数: 0 h-index: 0机构: Ctr Henri Becquerel, Dept Hematol, Rouen, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceWillems, Lise论文数: 0 引用数: 0 h-index: 0机构: Hosp Cochin, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceRaffoux, Emmanuel论文数: 0 引用数: 0 h-index: 0机构: Hop St Louis, Hematol Clin, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceBerthon, Celine论文数: 0 引用数: 0 h-index: 0机构: CHRU Lille, Dept Hematol, Lille, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceQuesnel, Bruno论文数: 0 引用数: 0 h-index: 0机构: CHU Lille, Serv Malad Sang, Hop Huriez, Lille, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceCarpentier, Antoine论文数: 0 引用数: 0 h-index: 0机构: Hosp St Louis, Dept Neurol, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceSallman, David A.论文数: 0 引用数: 0 h-index: 0机构: H Lee Moffitt Canc Ctr & Res Inst, Div Malignant Hematol, Tampa, FL USA H Lee Moffitt Canc Ctr & Res Inst, Dept Malignant Hematol, Tampa, FL USA Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceChevret, Sylvie论文数: 0 引用数: 0 h-index: 0机构: Paris 7 Univ, St Louis Hosp, Div Biostat, AP HP, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, FranceAdes, Lionel论文数: 0 引用数: 0 h-index: 0机构: Hop St Louis, Inst Univ Hematol, Paris, France Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, France论文数: 引用数: h-index:机构:
- [27] APR-246 targets pediatric acute lymphoblastic leukemia carrying mutant P53ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 117 - 117Demir, S.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, Germany Univ Ulm, Int Grad Sch Mol Med, D-89069 Ulm, Germany Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, GermanySelivanova, G.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Microbiol Tumor & Cell Biol, Stockholm, Sweden Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, GermanyTausch, E.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulm, Med Ctr, Dept Internal Med 3, D-89069 Ulm, Germany Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, GermanyWiesmueller, L.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulm, Med Ctr, Dept Obstet & Gynaecol, D-89069 Ulm, Germany Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, GermanyStilgenbauer, S.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulm, Med Ctr, Dept Internal Med 3, D-89069 Ulm, Germany Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, Germanyte Kronnie, G.论文数: 0 引用数: 0 h-index: 0机构: Univ Padua, Dept Womens & Childrens Hlth, Padua, Italy Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, GermanyDebatin, K. -M.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, Germany Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, GermanyMeyer, L.论文数: 0 引用数: 0 h-index: 0机构: Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, Germany Univ Ulm, Med Ctr, Dept Pediat & Adolescent Med, D-89069 Ulm, Germany
- [28] Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277Cell Death & Disease, 10Qiang Zhang论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)Vladimir J. N. Bykov论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)Klas G. Wiman论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)Joanna Zawacka-Pankau论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Department of Oncology and Pathology, Cancer Center Karolinska (CCK)
- [29] APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutationBritish Journal of Cancer, 2021, 125 : 1523 - 1532Teruyuki Kobayashi论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineTomoki Makino论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineKotaro Yamashita论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineTakuro Saito论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineKoji Tanaka论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineTsuyoshi Takahashi论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineYukinori Kurokawa论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineMakoto Yamasaki论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineKiyokazu Nakajima论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineEiichi Morii论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineHidetoshi Eguchi论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of MedicineYuichiro Doki论文数: 0 引用数: 0 h-index: 0机构: Osaka University,Department of Gastroenterological Surgery, Graduate School of Medicine
- [30] APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutationBRITISH JOURNAL OF CANCER, 2021, 125 (11) : 1523 - 1532Kobayashi, Teruyuki论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanMakino, Tomoki论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanYamashita, Kotaro论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanSaito, Takuro论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Yamasaki, Makoto论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanNakajima, Kiyokazu论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanMorii, Eiichi论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Pathol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanEguchi, Hidetoshi论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, JapanDoki, Yuichiro论文数: 0 引用数: 0 h-index: 0机构: Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan Osaka Univ, Grad Sch Med, Dept Surg Gastroenterol, Osaka, Japan