Endoscopic-assisted transorbital extended orbital exenteration: A multi-institutional preclinical study

被引：0

作者：

Roccuzzo, Giuseppe ^{[1
,2
,3
,4
,5
]}

Vyskocil, Erich ^{[3
,4
]}

Hirtler, Lena ^{[5
]}

Kandathil, Sam Augustine ^{[5
]}

Peris-Celda, Maria ^{[6
]}

Agosti, Edoardo ^{[7
]}

Kuan, Edward C. ^{[8
]}

Wang, Eric W. ^{[9
]}

Leong, Samuel ^{[10
]}

Sharma, Rishi ^{[11
]}

Borsetto, Daniele ^{[11
]}

Herman, Philippe ^{[12
]}

Vinciguerra, Alessandro ^{[12
]}

Verillaud, Benjamin ^{[12
]}

Bresson, Damien ^{[13
]}

Taboni, Stefano ^{[1
,2
]}

Erovic, Boban M. ^{[14
]}

Vural, Alperen ^{[15
]}

Dallan, Iacopo ^{[16
]}

Doglietto, Francesco ^{[17
]}

Schreiber, Alberto ^{[18
]}

Mattavelli, Davide ^{[18
]}

Rampinelli, Vittorio ^{[18
]}

Arosio, Alberto Daniele ^{[19
]}

Battaglia, Paolo ^{[19
]}

Valentini, Marco ^{[19
]}

Turri-Zanoni, Mario ^{[19
]}

Pozzi, Fabio ^{[20
]}

Volpi, Luca ^{[21
]}

Bignami, Maurizio ^{[21
]}

Castelnuovo, Paolo ^{[19
]}

Nicolai, Piero ^{[1
,2
]}

Ferrari, Marco ^{[1
,2
]}

机构：

[1] Padova Univ, Dept Neurosci DNS, Otolaryngol Sect, Padua, Italy

[2] Azienda Osped Univ Padova, Unit Otorhinolaryngol Head & Neck Surg, I-35128 Padua, Italy

[3] Gen Hosp, Dept Otorhinolaryngol, Vienna, Austria

[4] Med Univ Vienna, Vienna, Austria

[5] Med Univ Vienna, Ctr Anat & Cell Biol, Div Anat, Vienna, Austria

[6] Mayo Clin, Dept Neurosurg, Rochester, MN USA

[7] Univ Brescia, Div Neurosurg, Dept Med & Surg Specialties Radiol Sci & Publ Hlth, Brescia, Italy

[8] Univ Calif Irvine, Dept Otolaryngol Head & Neck Surg, Irvine, CA USA

[9] Univ Pittsburgh, Sch Med, Dept Otolaryngol, Pittsburgh, PA USA

[10] Liverpool Univ Hosp NHS Fdn Trust, Dept Ear Nose & Throat, Liverpool, England

[11] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Otolaryngol, Cambridge, England

[12] Univ Paris Cite, Hop Lariboisiere, Assistance Publ Hop Paris, Otorhinolaryngol & Skull Base Ctr, Paris, France

[13] Univ Paris Cite, Hop Lariboisiere, Assistance Publ Hop Paris, Dept Neurosurg, Paris, France

[14] Evangel Hosp, Inst Head & Neck Dis, Vienna, Austria

[15] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Otorhinolaryngol, Istanbul, Turkiye

[16] Azienda Osped Univ Pisana, Dept Otolaryngol Head & Neck Surg, Pisa, Italy

[17] Catholic Univ, Sch Med, Inst Neurosurg, Rome, Italy

[18] Univ Brescia, Unit Otorhinolaryngol Head & Neck Surg, Dept Surg Specialties Radiol Sci & Publ Hlth, Brescia, Italy

[19] Univ Insubria Varese, Osped Circolo, Dept Biotechnol & Life Sci, Div Otorhinolaryngol,ASST Sette Laghi, Varese, Italy

[20] Osped Circolo Fdn Macchi, ASST Sette Laghi, Dept Neurosurg, Varese, Italy

[21] Univ Insubria, Osped St Anna, Dept Otolaryngol Head & Neck Surg, ASST Lariana, Como, Italy

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2024年 / 46卷 / 09期

关键词：

extended orbital exenteration; orbital apex dissection; orbital encroaching malignancies; preclinical cadaveric study; sinonasal malignant tumors; CRANIOFACIAL RESECTION; SINONASAL; MANAGEMENT; RECONSTRUCTION; ANATOMY; SINUS; CANCER; TUMORS; BAND;

D O I：

10.1002/hed.27858

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

BackgroundSinonasal malignancies with orbital invasion have dismal prognosis even when treated with orbital exenteration (OE). Sugawara et al. developed a surgical strategy called "extended-OE (EOE)," showing encouraging outcomes. We hypothesized that a similar resection is achievable under endoscopic guidance through the exenterated orbit (endoscopic-EOE).MethodsThe study was conducted in three institutions: University of Vienna; Mayo Clinic; University of Insubria; 48 orbital dissections were performed. A questionnaire was developed to evaluate feasibility and safety of each step, scoring from 1 to 10, ("impossible" to "easy," and "high risk" to "low risk," respectively), most likely complication(s) were hypothesized.ResultsThe step-by-step technique is thoroughly described. The questionnaire was answered by 25 anterior skull base surgeons from six countries. Mean, median, range, and interquartile range of both feasibility and safety scores are reported.ConclusionsEndoscopic-EOE is a challenging but feasible procedure. Clinical validation is required to assess real-life outcomes.

引用

页码：2327 / 2339

页数：13

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