Radon and lung cancer: Current status and future prospects

被引：1

作者：

Liu, Yan ^{[1
]}

Xu, Yanqing ^{[1
]}

Xu, Wei ^{[2
]}

He, Zhengzhong ^{[3
]}

Fu, Cong ^{[1
]}

Du, Fen ^{[4
]}

机构：

[1] Wuhan Univ, Sch Remote Sensing & Informat Engn, Wuhan 430079, Hubei, Peoples R China

[2] Wuhan Univ, Renmin Hosp, Hlth Management Ctr, Wuhan 430060, Hubei, Peoples R China

[3] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Hunan, Peoples R China

[4] Wuhan Univ, TaiKang Med Sch, Sch Basic Med Sci, Dept Biochem & Mol Biol, Wuhan 430071, Hubei, Peoples R China

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2024年 / 198卷

关键词：

Radon; Lung cancer; Epidemiology; Carcinogenesis; Radon risk zone; RESIDENTIAL RADON; INDOOR RADON; EXHALATION RATE; RISK-ASSESSMENT; URANIUM MINERS; EXPOSED MINERS; SOIL; PREDICTION; P53; MORTALITY;

D O I：

10.1016/j.critrevonc.2024.104363

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Beyond tobacco smoking, radon takes its place as the second most significant contributor to lung cancer, excluding hereditary and other biologically related factors. Radon and its byproducts play a pivotal role in exposing humans to elevated levels of natural radiation. Approximately 10-20 % of lung cancer cases worldwide can be attributed to radon exposure, leading to between 3 % and 20 % of all lung cancer-related deaths. Nevertheless, a knowledge gap persists regarding the association between radon and lung cancer, impeding radon risk reduction initiatives globally. This review presents a comprehensive overview of the current state of research in epidemiology, cell biology, dosimetry, and risk modeling concerning radon exposure and its relevance to lung cancer. It also delves into methods for measuring radon concentrations, monitoring radon risk zones, and identifying priorities for future research.

引用

页数：13

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