Innovative surgical techniques in the intestine and multivisceral transplant
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作者:
Abreu, Phillipe
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Univ Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USAUniv Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USA
Abreu, Phillipe
[1
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Manzi, Joao
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Univ Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USA
Univ Sao Paulo, Med Sch, Sao Paulo, BrazilUniv Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USA
Manzi, Joao
[1
,2
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Vianna, Rodrigo
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Univ Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USAUniv Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USA
Vianna, Rodrigo
[1
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机构:
[1] Univ Miami, Jackson Mem Hosp, Miami Transplant Inst, Dept Surg, Miami, FL USA
Purpose of reviewThis timely review delves into the evolution of multivisceral transplantation (MVT) over the past six decades underscoring how advancements in surgical techniques and immunosuppression have driven transformation, to provide insight into the historical development of MVT, shedding light on its journey from experimentation to a valuable clinical approach.Recent findingsThe review presents contemporary enhancements in surgical methods within the context of intestinal transplantation. The versatility of MVT is emphasized, accommodating diverse organ combinations and techniques. Both isolated intestinal transplantation (IIT) and MVT have seen expanded indications, driven by improved parenteral nutrition, transplantation outcomes, and surgical innovations. Surgical techniques are tailored based on graft type, with various approaches for isolated transplantation. Preservation strategies and ostomy techniques are also covered, along with graft assessment advancements involving donor-specific antibodies.SummaryThis review's findings underscore the remarkable evolution of MVT from experimental origins to a comprehensive clinical practice. The progress in surgical techniques and immunosuppression has broadened the spectrum of patients who can benefit from intestinal transplant, including both IIT and MVT. The expansion of indications offers hope to patients with complex gastrointestinal disorders. The detection of donor-specific antibodies in graft assessment advances diagnostic accuracy, ultimately improving patient outcomes.
机构:
Stanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Stanford Univ, Div Gastroenterol & Hepatol, 430 Broadway St,3rd Floor, Redwood City, CA 94063 USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Kwong, Allison J.
Schnellinger, Erin
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机构:
United Network Organ Sharing, Richmond, VA USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Schnellinger, Erin
Foutz, Julia
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United Network Organ Sharing, Richmond, VA USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Foutz, Julia
Cafarella, Matt
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机构:
United Network Organ Sharing, Richmond, VA USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Cafarella, Matt
Nagai, Shunji
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机构:
Henry Ford Hlth, Detroit, MI USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Nagai, Shunji
Biggins, Scott W.
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机构:
Univ Pittsburgh, Pittsburgh, PA USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Biggins, Scott W.
Pomposelli, James
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机构:
Univ Colorado Anschutz Med Ctr, Aurora, CO USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA
Pomposelli, James
Trotter, James
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机构:
Baylor Univ, Med Ctr, Baylor Scott & White Hlth, Dallas, TX USAStanford Univ, Div Gastroenterol & Hepatol, Palo Alto, CA USA