Guidelines of care for the management of acne vulgaris

被引:71
|
作者
Reynolds, Rachel, V [1 ]
Yeung, Howa [2 ]
Cheng, Carol E. [3 ]
Cook-Bolden, Fran [4 ]
Desai, Seemal R. [5 ,6 ]
Druby, Kelly M. [7 ]
Freeman, Esther E. [8 ]
Keri, Jonette E. [9 ,10 ]
Gold, Linda F. Stein [11 ]
Tan, Jerry K. L. [12 ,13 ]
Tollefson, Megha M. [14 ,15 ]
Weiss, Jonathan S. [2 ,16 ]
Wu, Peggy A. [17 ]
Zaenglein, Andrea L. [18 ,19 ]
Han, Jung Min [20 ]
Barbieri, John S. [21 ]
机构
[1] Beth Israel Deaconess Med Ctr, Dept Dermatol, Boston, MA USA
[2] Emory Univ, Sch Med, Dept Dermatol, Atlanta, GA USA
[3] Univ Calif Los Angeles, Dept Med, Div Dermatol, Los Angeles, CA USA
[4] Weill Cornell Med, Dept Dermatol, New York, NY USA
[5] Innovat Dermatol, Plano, TX USA
[6] Univ Texas Southwestern Med Ctr, Dept Dermatol, Dallas, TX USA
[7] Penn State Hlth Hampden Med Ctr, Enola, PA USA
[8] Massachusetts Gen Hosp, Dept Dermatol, Boston, MA USA
[9] Univ Miami, Miller Sch Med, Miami, FL USA
[10] Miami VA Med Ctr, Miami, FL USA
[11] Henry Ford Hlth, Dept Dermatol, Detroit, MI USA
[12] Western Univ, Londoni, ON, Canada
[13] Windsor Clin Res Inc, Windsor, ON, Canada
[14] Mayo Clin, Dept Dermatol, Rochester, MN USA
[15] Mayo Clin, Dept Pediat, Rochester, MN USA
[16] Georgia Dermatol Partners, Snellville, GA USA
[17] Univ Calif Davis, Dept Dermatol, Sacramento, CA USA
[18] Penn State Hershey Med Ctr, Dept Dermatol, Hershey, PA USA
[19] Penn State Hershey Med Ctr, Dept Pediat, Hershey, PA USA
[20] Amer Acad Dermatol, 9500 Bryn Mawr Ave,Suite 500, Rosemont, IL 60018 USA
[21] Brigham & Womens Hosp, Dept Dermatol, Boston, MA USA
关键词
Acne; acne vulgaris; adapalene; antiandrogens; antibiotics; azelaic acid; azithromycin; benzoyl peroxide; clascoterone; clindamycin; contraceptives; corticosteroids; Cutibacterium acnes; diet and acne; doxycycline; erythromycin; grading and classification of acne; guidelines; hormonal therapy; isotretinoin; light therapies; microbiological and endocrine testing; minocycline; retinoids; salicylic acid; sarecycline; spironolactone; tazarotene; treatment; tretinoin; trifarotene; INFLAMMATORY-BOWEL-DISEASE; QUALITY-OF-LIFE; TO-SEVERE ACNE; ONCE-DAILY TREATMENT; CLINDAMYCIN PHOSPHATE 1.2-PERCENT; TAZAROTENE 0.045-PERCENT LOTION; TRETINOIN 0.05-PERCENT LOTION; BENZOYL PEROXIDE 3.75-PERCENT; 20; MU-G; TOPICAL ISOTRETINOIN 0.05-PERCENT;
D O I
10.1016/j.jaad.2023.12.017
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Acne vulgaris commonly affects adults, adolescents, and preadolescents aged 9 years or older. Objective: The objective of this study was to provide evidence -based recommendations for the management of acne. Methods: A work group conducted a systematic review and applied the Grading of Recommendations, Assessment, Development, and Evaluation approach for assessing the certainty of evidence and formulating and grading recommendations. Results: This guideline presents 18 evidence -based recommendations and 5 good practice statements. Strong recommendations are made for benzoyl peroxide, topical retinoids, topical antibiotics, and oral doxycycline. Oral isotretinoin is strongly recommended for acne that is severe, causing psychosocial burden or scarring, or failing standard oral or topical therapy. Conditional recommendations are made for topical clascoterone, salicylic acid, and azelaic acid, as well as for oral minocycline, sarecycline, combined oral contraceptive pills, and spironolactone. Combining topical therapies with multiple mechanisms of action, limiting systemic antibiotic use, combining systemic antibiotics with topical therapies, and adding intralesional corticosteroid injections for larger acne lesions are recommended as good practice statements. Limitations: Analysis is based on the best available evidence at the time of the systematic review. Conclusions: These guidelines provide evidence -based recommendations for the management of acne vulgaris.
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页码:1006.e1 / 1006.e30
页数:30
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