Posttranslational Arginylation Regulates Striated Muscle Function

被引：8

作者：

Leite, Felipe de Souza ^{[1
]}

Kashina, Anna ^{[2
]}

Rassier, Dilson E. ^{[1
]}

机构：

[1] McGill Univ, Dept Kinesiol & Phys Educ Phys & Physiol, 475 Pine Ave W,Room 308, Montreal, PQ H2W 1S4, Canada

[2] Univ Penn, Sch Vet Med, Dept Anim Biol, Philadelphia, PA 19104 USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2016年 / 44卷 / 03期

基金：

美国国家卫生研究院; 加拿大健康研究院;

关键词：

myosin; actin; titin; arginylation; posttranslational modification; BINDING PROTEIN-C; SARCOMERIC Z-DISK; ALPHA-ACTININ; MYOSIN; TITIN; TRANSFERASE; DOMAIN; HEART; CYTOSKELETON; EXPRESSION;

D O I：

10.1249/JES.0000000000000079

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

In this article, we propose the hypothesis that the posttranslational arginylation of proteins, a process catalyzed by the enzyme arginyl-tRNA-transferase, regulates active and passive force generation in striated muscles. Specifically, we propose that proteins essential for muscle contraction and force production are regulated by arginylation, including myosin heavy chain, troponin, actin, and titin filaments.

引用

页码：98 / 103

页数：6

共 50 条

[41] Impact of the Birth Transition on Striated Muscle Function in Normal Development
Hagen, Matthew W.
Louey, Samantha
Alaniz, Sarah
Lindner, Jonathan
Jonker, Sonnet
FASEB JOURNAL, 2022, 36
[42] STRUCTURAL STUDIES ON M LINE STRIATED MUSCLE AND A PROPOSED FUNCTION
DOSREMED.CG
JOURNAL OF ANATOMY, 1970, 106 : 195 - &
[43] Fatigue conditions alter sarcoplasmic reticulum function of striated muscle
Andrews, MAW
Nosek, TM
CARDIAC SARCOPLASMIC RETICULUM FUNCTION AND REGULATION OF CONTRACTILITY, 1998, 853 : 300 - 303
[44] Ate1-mediated posttranslational arginylation is essential for stress response regulation and mutagenesis suppression
Kumar, Akhilesh
Birnbaum, Michael D.
Morgan, William
Zhang, Fangliang
FASEB JOURNAL, 2016, 30
[45] EFFECTS OF CERTAIN AUTONOMIC BLOCKING AGENTS ON STRIATED MUSCLE FUNCTION
JEPSON, RP
SIMEONE, FA
LYNN, RB
AMERICAN JOURNAL OF PHYSIOLOGY, 1953, 173 (01): : 70 - 74
[46] Structure-function relation of the myosin motor in striated muscle
Reconditi, M
Linari, M
Lucii, L
Stewart, A
Sun, YB
Narayanan, T
Irving, T
Piazzesi, G
Irving, M
Lombardi, V
COMMUNICATIVE CARDIAC CELL, 2005, 1047 : 232 - 247
[47] STRUCTURE-FUNCTION ANALYSIS OF STRIATED-MUSCLE MYOSIN
SWEENEY, HL
YANG, ZH
STULL, JT
LEINWAND, L
FENG, H
FAUST, L
JOURNAL OF CELLULAR BIOCHEMISTRY, 1994, : 512 - 512
[48] FORCE GENERATION AS A FUNCTION OF MYOFILAMENT SPACING IN STRIATED-MUSCLE
APRIL, EW
MAUGHAN, DW
ANATOMICAL RECORD, 1985, 211 (03): : A11 - A11
[49] Actin dynamics at pointed ends regulates thin filament length in striated muscle
Littlefield, R
Almenar-Queralt, A
Fowler, VM
NATURE CELL BIOLOGY, 2001, 3 (06) : 544 - 551
[50] Actin dynamics at pointed ends regulates thin filament length in striated muscle
Ryan Littlefield
Angels Almenar-Queralt
Velia M. Fowler
Nature Cell Biology, 2001, 3 : 544 - 551

← 1 2 3 4 5 →