Chinese Multidisciplinary Expert Consensus on Immune Checkpoint Inhibitor-Based Combination Therapy for Hepatocellular Carcinoma (2023 Edition)

被引:0
|
作者
Liu, Xiufeng [1 ]
Lu, Yinying [2 ]
Zhou, Weiping [3 ]
Peng, Tao [4 ]
Zhou, Jie [5 ]
Bi, Huaqiang [6 ]
Xia, Feng [6 ]
Chen, Xiaoping [7 ]
机构
[1] Jinling Hosp, PLA Canc Ctr, Dept Med Oncol, Nanjing, Peoples R China
[2] Peoples Liberat Army Gen Hosp, Comprehens Liver Canc Ctr, Med Ctr 5, Beijing, Peoples R China
[3] Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepat Surg 3, Shanghai, Peoples R China
[4] Guangxi Med Univ, Affiliated Hosp 1, Hepatobiliary Surg Dept, Nanning, Peoples R China
[5] Southern Med Univ, Nanfang Hosp, Dept Gen Surg, Div Hepatobiliopancreat Surg & Liver Transplantat, Guangzhou, Peoples R China
[6] Army Med Univ, Hosp 1, Dept Hepatobiliary Surg, Chongqing, Peoples R China
[7] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Hepatobiliary Surg, Wuhan, Peoples R China
关键词
Hepatocellular carcinoma; Immunotherapy; Combination therapy; Immune checkpoint inhibitors; Multidisciplinary team; Consensus; TENOFOVIR DISOPROXIL FUMARATE; OPEN-LABEL; DOUBLE-BLIND; CONVERSION THERAPY; SINTILIMAB PLUS; SORAFENIB; PHASE-3; IMMUNOTHERAPY; ATEZOLIZUMAB; MULTICENTER;
D O I
10.1159/000535496
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Immune checkpoint inhibitor (ICI)-based combination therapy modalities for hepatocellular carcinoma (HCC) have achieved significant efficacy in clinical research and practice and have become the mainstay for the treatment of unresectable HCC. Summary: To better help clinicians use combination immunotherapy drugs and regimens rationally, effectively, and safely, the editorial board facilitated a discussion with multidisciplinary experts in the field, adopted the "Delphi" consensus formation method, and finally revised and completed the "Chinese Multidisciplinary Expert Consensus on the Immune Checkpoint Inhibitors (ICIs)-Based Combination Therapy for Hepatocellular Carcinoma (2023 Edition)" on the basis of the 2021 edition. Key Messages: This consensus primarily focuses on the principles and methods of clinical practice of combination therapy based on ICIs, aiming to summarize the recommendations for clinical application based on the latest research and expert experience and provide application guidance for clinicians.
引用
收藏
页码:355 / 375
页数:21
相关论文
共 50 条
  • [31] Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma
    Cheng, Ann-Lii
    Hsu, Chiun
    Chan, Stephen L.
    Choo, Su-Pin
    Kudo, Masatoshi
    JOURNAL OF HEPATOLOGY, 2020, 72 (02) : 307 - 319
  • [32] Current Landscape of Immune Checkpoint Inhibitor Therapy for Hepatocellular Carcinoma
    Ruff, Samantha M.
    Manne, Ashish
    Cloyd, Jordan M.
    Dillhoff, Mary
    Ejaz, Aslam
    Pawlik, Timothy M.
    CURRENT ONCOLOGY, 2023, 30 (06) : 5863 - 5875
  • [33] Current Landscape of Immune Checkpoint Inhibitor Therapy for Hepatocellular Carcinoma
    Machairas, Nikolaos
    Tsilimigras, Diamantis, I
    Pawlik, Timothy M.
    CANCERS, 2022, 14 (08)
  • [34] Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements
    Sun, Yongkun
    Zhang, Wen
    Bi, Xinyu
    Yang, Zhengqiang
    Tang, Yu
    Jiang, Liming
    Bi, Feng
    Chen, Minshan
    Cheng, Shuqun
    Chi, Yihebali
    Han, Yue
    Huang, Jing
    Huang, Zhen
    Ji, Yuan
    Jia, Liqun
    Jiang, Zhichao
    Jin, Jing
    Jin, Zhengyu
    Li, Xiao
    Li, Zhiyu
    Liang, Jun
    Liu, Lianxin
    Liu, Yunpeng
    Lu, Yinying
    Lu, Shichun
    Meng, Qinghua
    Niu, Zuoxing
    Pan, Hongming
    Qin, Shukui
    Qu, Wang
    Shao, Guoliang
    Shen, Feng
    Song, Tianqiang
    Song, Yan
    Tao, Kaishan
    Tian, Aiping
    Wang, Jianhua
    Wang, Wenling
    Wang, Zhe
    Wu, Liqun
    Xia, Feng
    Xing, Baocai
    Xu, Jianming
    Xue, Huadan
    Yan, Dong
    Yang, Lin
    Ying, Jianming
    Yun, Jingping
    Zeng, Zhaochong
    Zhang, Xuewen
    LIVER CANCER, 2022, 11 (03) : 192 - 208
  • [35] Immune checkpoint inhibitor-based therapy for advanced acral and mucosal melanoma
    Mori, Tatsuhiko
    Izumi, Teruaki
    Doi, Reiichi
    Kamimura, Anna
    Takai, Sayaka
    Teramoto, Yukiko
    Nakamura, Yasuhiro
    EXPERIMENTAL DERMATOLOGY, 2023, 32 (03) : 276 - 289
  • [37] IMPACT OF CORTICOSTEROID ADMINISTRATION ON TREATMENT EFFECTIVENESS IN PATIENTS WITH ADVANCED RENAL CELL CARCINOMA TREATED WITH IMMUNE CHECKPOINT INHIBITOR-BASED COMBINATION THERAPY
    Yoshino, Maki
    Ishihara, Hiroki
    Nagahisa, Chika
    Nemoto, Yuki
    Ishiyama, Ryo
    Ikeda, Takeshi
    Kobari, Yuki
    Tachibana, Hidekazu
    Fukuda, Hironori
    Yoshida, Kazuhiko
    Shimmura, Hiroaki
    Hashimoto, Yasunobu
    Kondo, Tsunenori
    Takagi, Toshio
    JOURNAL OF UROLOGY, 2024, 211 (05): : E146 - E147
  • [38] Association Between Kidney Function and Outcomes Following Immune Checkpoint Inhibitor-Based Combination Therapy in Patients With Advanced Renal Cell Carcinoma
    Ishihara, Hiroki
    Nemoto, Yuki
    Tachibana, Hidekazu
    Ikeda, Takashi
    Fukuda, Hironori
    Yoshida, Kazuhiko
    Kobayashi, Hirohito
    Iizuka, Junpei
    Shimmura, Hiroaki
    Hashimoto, Yasunobu
    Kondo, Tsunenori
    Takagi, Toshio
    CLINICAL GENITOURINARY CANCER, 2024, 22 (02) : 549 - 557.e5
  • [39] Immune checkpoint inhibitor-based therapy for advanced clear cell renal cell carcinoma: A narrative review
    Liu, Yi-Fu
    Zhang, Zhi-Cheng
    Wang, Si-Yuan
    Fu, Sheng-Qiang
    Cheng, Xiao-Feng
    Chen, Ru
    Sun, Ting
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 110
  • [40] Chinese expert consensus on the diagnosis and treatment of hepatocellular carcinoma with microvascular invasion (2024 edition)
    Sun, Juxian
    Xia, Yong
    Shen, Feng
    Cheng, Shuqun
    Chinese Association Liver Cancer Chinese Medical Doctor Association
    HEPATOBILIARY SURGERY AND NUTRITION, 2024,