Safety and Intracranial Activity of Adagrasib in Patients With KRASG12C-Mutated Non-Small-Cell Lung Cancer and Untreated CNS Metastases in the KRYSTAL-1 Trial: A Case Series

被引：2
|
作者：
Bernstein, Ezra [1 ]
Luo, Jia [2 ]
Wang, Kaiwen [3 ]
Negrao, Marcelo V. [4 ]
Janne, Pasi A. [2 ]
Sabari, Joshua K. [5 ]
机构：
[1] NYU, Langone Dept Internal Med, 251 East 33rd St, New York, NY 10016 USA
[2] Dana Faber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA USA
[3] Univ Texas MD Anderson Canc Ctr, Div Pharm, Houston, TX USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Thorac & Head & Neck Med Oncol, Houston, TX USA
[5] NYU Langone Hlth, Perlmutter Canc Ctr, New York, NY USA
来源：
JCO PRECISION ONCOLOGY | 2024年 / 8卷
关键词：
D O I：
10.1200/PO.23.00447
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Case series demonstrates activity of adagrasib in untreated CNS metastases across multiple scenarios.
引用
收藏
页数：7
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