Opercular myoclonic-anarthric status (OMASE) secondary to anti-Hu paraneoplastic neurological syndrome

被引：0

作者：

Romero, Cesar ^{[1
]}

Quijada, Alonso ^{[1
]}

Abudinen, Gabriel ^{[1
]}

Cespedes, Catherine ^{[1
]}

Aguilera, Ledda ^{[1
]}

机构：

[1] Univ Chile, Hosp Clin, Neurol & Neurosurg Dept, Santiago, Chile

来源：

EPILEPSY & BEHAVIOR REPORTS | 2024年 / 27卷

关键词：

Paraneoplastic neurological syndrome; Autoimmune encephalitis; Status epilepticus; OMASE; Anti-Hu IgG; GLUTAMIC-ACID DECARBOXYLASE; EPILEPSIA PARTIALIS CONTINUA; STATUS EPILEPTICUS; ANTIBODIES;

D O I：

10.1016/j.ebr.2024.100703

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Focal Opercular Myoclonic - Anarthric Status Epilepticus (OMASE) is a rare form of focal motor status epilepticus caused by several etiologies. It is characterized by fluctuating dysarthria and epileptic myoclonus involving the bilateral glossopharyngeal musculature. We present the case of a 52-year-old woman who experienced gradual and progressive paralysis and myoclonus of facial and bulbar muscles; additional tests revealed the presence of right breast ductal adenocarcinoma and positive serum anti-Hu and anti-GAD65 antibodies. High doses of steroid pulses, anti-seizure therapy, and rituximab partially controlled myoclonus; the tumor resection improved dysphagia and dysarthria.

引用

页数：4

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