Synthesis of Novel Sulfonamide Derivatives Featuring 1-(Methylsulfonyl)-4-(2,3,4-Trimethoxybenzyl)Piperazine Core Structures

被引：0
|
作者：
Ivanov, Iliyan [1 ]
Manolov, Stanimir [1 ]
Bojilov, Dimitar [1 ]
Dimitrova, Diyana [1 ]
Nedialkov, Paraskev [2 ]
机构：
[1] Paisij Hilendarski Univ Plovdiv, Fac Chem, Dept Organ Chem, 24 Tsar Assen Str, Plovdiv 4000, Bulgaria
[2] Med Univ Sofia, Fac Pharm, Dept Pharmacognosy, 2 Dunav Str, Sofia 1000, Bulgaria
来源：
MOLBANK | 2024年 / 2024卷 / 03期
关键词：
trimetazidine; 1-(2,3,4-trimethoxybenzyl)piperazine; sulfonamides; methanesulfonyl chloride; benzenesulfonyl chloride; phenylmethanesulfonyl chloride; angina pectoris; doping; TRIMETAZIDINE; DRUGS;
D O I：
10.3390/M1879
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein we report the synthesis of three novel sulfonamide derivatives of trimetazidine-medication primarily used to treat angina pectoris. The new compounds have been fully characterized with their melting point, 1H- and 13C-NMR, UV, and mass spectrometry. The collected data confirm the successful synthesis and structural integrity of the new molecules.
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页数：5
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