Electrochemical Benzylic C-H Amination via N-Aminopyridinium

被引：1
|
作者：
Liu, Jingwei [1 ]
Du, Jinyao [1 ]
Zhang, Lin-Bao [1 ]
Li, Ming [1 ]
Guo, Weisi [1 ]
机构：
[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 09期
关键词：
C(SP(3))-H BONDS; SALTS;
D O I：
10.1021/acs.joc.4c00502
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An electrochemical protocol for benzylic C(sp(3))-H aminopyridylation via direct C-H/N-H cross-coupling of alkylarenes with N-aminopyridinium triflate has been developed. This method features excellent site-selectivity, broad substrate scope, redox reagent-free and facile scalability. The generated benzylaminopyridiniums can be readily converted to benzylamines via electroreductive N-N bond cleavage.
引用
收藏
页码：6465 / 6473
页数：9
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