A woman in her 40s presented with thoracic banding dysaesthesia and lower motor neuron weakness. Spinal imaging revealed a short segment of transverse myelitis and neurophysiology was suggestive of concurrent acute inflammatory demyelinating polyneuropathy. The patient improved with consecutive intravenous immunoglobulin and methylprednisolone treatment. Acute inflammatory demyelinating polyneuropathy is a progressive immune-mediated peripheral neuropathy which responds to intravenous immunoglobulin or plasmapheresis, whereas transverse myelitis is a central inflammatory syndrome usually treated with corticosteroid. We highlight differentiating features of the clinical presentation and the utility of investigations such as neurophysiology and MRI along with a review of treatment and the role for corticosteroid therapy.
机构:
Kawasaki Med Sch, Dept Neurol, Okayama, Japan
Kawasaki Med Sch, Gen Med Ctr, Dept Gen Internal Med 1, Okayama, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan
Kurokawa, Katsumi
Sonoo, Masahiro
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Teikyo Univ, Sch Med, Dept Neurol, Tokyo, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan
Sonoo, Masahiro
Yamamoto, Tetsuya
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Kawasaki Med Sch, Gen Med Ctr, Dept Kawasaki Clin Educ & Training, Okayama, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan
Yamamoto, Tetsuya
Yamada, Haruki
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Kawasaki Med Sch, Gen Med Ctr, Dept Gen Internal Med 1, Okayama, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan
Yamada, Haruki
Hemmi, Shoji
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Kawasaki Med Sch, Dept Neurol, Okayama, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan
Hemmi, Shoji
Tomoda, Koichi
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Kawasaki Med Sch, Gen Med Ctr, Dept Gen Internal Med 1, Okayama, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan
Tomoda, Koichi
Sunada, Yoshihide
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Kawasaki Med Sch, Dept Neurol, Okayama, JapanKawasaki Med Sch, Dept Neurol, Okayama, Japan