Considerations for anti-PD1-based first-line treatment of Hodgkin lymphoma

被引:1
|
作者
Broeckelmann, Paul J. [1 ,2 ,3 ,4 ,5 ,6 ]
机构
[1] Univ Cologne, Dept Internal Med 1, Fac Med, Cologne, Germany
[2] Univ Cologne, Univ Hosp Cologne, Ctr Integrated Oncol Aachen Bonn Cologne Duesseldo, Cologne, Germany
[3] German Hodgkin Study Grp GHSG, Cologne, Germany
[4] Max Planck Inst Biol Ageing, Max Planck Res Grp Mech DNA Repair, Cologne, Germany
[5] Univ Hosp Cologne, Fac Med, Dept Internal Med 1, Kerpener Str 62, D-50937 Cologne, Germany
[6] Univ Hosp Cologne, Ctr Integrated Oncol Aachen Bonn Cologne Duesseldo, Kerpener Str 62, D-50937 Cologne, Germany
关键词
anti-PD1; Hodgkin lymphoma; pembrolizumab;
D O I
10.1111/bjh.19534
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Anti-PD1-based first-line treatment holds great promise in classical Hodgkin lymphoma. The management of immune-related adverse events in the context of time-limited combined checkpoint blockade and chemotherapy administered in curative intent is a challenge. Kuczmarski and Lynch provide a case-based approach to key toxicities observed in this setting.
引用
收藏
页码:22 / 24
页数:3
相关论文
共 50 条
  • [21] Progression-free survival: a true endpoint in first-line treatment for classic Hodgkin Lymphoma?
    Yamauchi, N.
    Maruyama, D.
    ANNALS OF ONCOLOGY, 2025, 36 (04) : 356 - 358
  • [22] Clinical biomarkers of response to anti-PD-1 first-line treatment in an Italian patient cohort
    Di Pietro, Francesca Romana
    Verkhovskaia, Sofia
    Mastroeni, Simona
    Carbone, Maria Luigia
    Abeni, Damiano
    Di Rocco, Zorika Christiana
    Sama, Nicola
    Zappala, Albina Rita
    Marchetti, Paolo
    De Galitiis, Federica
    Failla, Cristina Maria
    Fortes, Cristina
    JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 19 (SUPPL 1)
  • [23] Positron emission tomography-adapted therapy for first-line treatment in individuals with Hodgkin lymphoma
    Sickinger, Marie-Therese
    von Tresckow, Bastian
    Kobe, Carsten
    Engert, Andreas
    Borchmann, Peter
    Skoetz, Nicole
    COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2015, (01):
  • [24] The role of PET in the first-line treatment of the most common subtypes of non-Hodgkin lymphoma
    Barrington, Sally F.
    Trotman, Judith
    LANCET HAEMATOLOGY, 2021, 8 (01): : E80 - E93
  • [25] SEGHI Study: Defining the Best Surveillance Strategy in Hodgkin Lymphoma after First-Line Treatment
    Bastos Oreiro, Mariana
    Martin, Reyes
    Gomez, Pilar
    Lopez Munoz, Nieves
    Rodriguez, Antonia
    Liebana, Marta
    Navarro, Belen
    Sanchez-Gonzalez, Blanca
    Mari, Pilar
    Perez de Oteiza, Jaime
    Gutierrez, Antonio
    Bento, Leyre
    Domingo Domenech, Eva
    Vidal, Maria Jesus
    Del Campo, Raquel
    Perez Ceballos, Elena
    Infante, Maria
    Roldan, Alicia
    Garcia Belmonte, Daniel
    Santero, Miriam
    Sureda, Anna
    Sanz, Ramon Garcia
    CANCERS, 2021, 13 (10)
  • [26] Immune-checkpoint inhibition as first-line therapy for Hodgkin lymphoma
    Alencar, Alvaro J.
    Moskowitz, Craig H.
    NATURE REVIEWS CLINICAL ONCOLOGY, 2019, 16 (10) : 599 - 600
  • [27] Immune-checkpoint inhibition as first-line therapy for Hodgkin lymphoma
    Alvaro J. Alencar
    Craig H. Moskowitz
    Nature Reviews Clinical Oncology, 2019, 16 : 599 - 600
  • [29] The efficacy and safety of chemotherapy with or without anti-PD-1 for the first-line treatment of advanced urothelial carcinoma
    Han, Fuxin
    Wu, Zhaozhen
    Chen, Jiaxin
    Liu, Meicen
    Hu, Yi
    CANCER MEDICINE, 2023, 12 (23): : 21129 - 21137
  • [30] Anti PD-1 Checkpoint Inhibitor As a First-Line Treatment for Advanced Cutaneous Squamous Cell Carcinoma
    Bopota, Katerina
    Donnelly, Oliver
    Borumandi, Farzad
    JOURNAL OF CRANIOFACIAL SURGERY, 2023, 34 (03) : E247 - E249