Considerations for anti-PD1-based first-line treatment of Hodgkin lymphoma

被引:1
|
作者
Broeckelmann, Paul J. [1 ,2 ,3 ,4 ,5 ,6 ]
机构
[1] Univ Cologne, Dept Internal Med 1, Fac Med, Cologne, Germany
[2] Univ Cologne, Univ Hosp Cologne, Ctr Integrated Oncol Aachen Bonn Cologne Duesseldo, Cologne, Germany
[3] German Hodgkin Study Grp GHSG, Cologne, Germany
[4] Max Planck Inst Biol Ageing, Max Planck Res Grp Mech DNA Repair, Cologne, Germany
[5] Univ Hosp Cologne, Fac Med, Dept Internal Med 1, Kerpener Str 62, D-50937 Cologne, Germany
[6] Univ Hosp Cologne, Ctr Integrated Oncol Aachen Bonn Cologne Duesseldo, Kerpener Str 62, D-50937 Cologne, Germany
关键词
anti-PD1; Hodgkin lymphoma; pembrolizumab;
D O I
10.1111/bjh.19534
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Anti-PD1-based first-line treatment holds great promise in classical Hodgkin lymphoma. The management of immune-related adverse events in the context of time-limited combined checkpoint blockade and chemotherapy administered in curative intent is a challenge. Kuczmarski and Lynch provide a case-based approach to key toxicities observed in this setting.
引用
收藏
页码:22 / 24
页数:3
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