The MARIPOSA trials - implications for the treatment of EGFR-mutant NSCLC

被引:1
|
作者
Ardeshir-Larijani, Fatemeh [1 ]
Ramalingam, Suresh S. [1 ]
机构
[1] Emory Univ, Sch Med, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA 30322 USA
关键词
D O I
10.1038/s41571-024-00938-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In the past 2 years, substantial improvements have been made in the management of advanced-stage EGFR-mutant non-small-cell lung cancer. Recent studies have suggested added benefit from the combination of third-generation tyrosine-kinase inhibitors with either chemotherapy or a bispecific antibody targeting EGFR and MET. Herein, we summarize these advances and their implications for clinical practice.
引用
收藏
页码:767 / 768
页数:2
相关论文
共 50 条
  • [31] Rociletinib-associated cataracts in EGFR-mutant NSCLC.
    Piotrowska, Zofia
    Liu, Erica
    Logan, Jennifer
    Chow, Jessica
    Woreta, Fasika A.
    Muzikansky, Alona
    Stober, Lisa
    Wanat, Alexandra Carly
    Goodwin, Kelly
    Azzoli, Christopher G.
    Temel, Jennifer S.
    Heis, Rebecca Suk
    Shaw, Alice Tsang
    Engelman, Jeffrey A.
    Kopani, Kamden
    Sequist, Lecia V.
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [32] Characteristics and outcomes of Latino patients with EGFR-mutant NSCLC.
    Mathew, Matthen
    Lagos, Galina G.
    Rao, Nisha
    Asmar, Ramsey Nicholas
    Liu, Xinhua
    Rizvi, Naiyer A.
    Orjuela, Manuela A.
    Shu, Catherine A.
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [33] Does TMB Impact the Effectiveness of TKIs in EGFR-Mutant NSCLC?
    Cheng, Michael L.
    Oxnard, Geoffrey R.
    CLINICAL CANCER RESEARCH, 2019, 25 (03) : 899 - 900
  • [34] Pulse Dose Erlotinib and Zuckerguss Improvement in EGFR-Mutant NSCLC
    Mehta, Pareen
    Hamid, Omid
    Klempner, Samuel J.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (12) : 1857 - 1858
  • [35] Induction osimertinib in EGFR-mutant stage IIIA/B NSCLC
    Kian, W.
    Roisman, L. C.
    Dudnik, J.
    Chernomordikov, L.
    Allen, A. M.
    Corn, B.
    Dudnik, E.
    Rosenberg, S. K.
    Zemel, M.
    Lavrenkov, K.
    Peled, N.
    ANNALS OF ONCOLOGY, 2021, 32 : S941 - S941
  • [36] Sequence, Treat, Repeat: Addressing Resistance in EGFR-Mutant NSCLC
    Klempner, Samuel J.
    Hata, Aaron N.
    JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (11) : 1875 - 1877
  • [37] Lazertinib vs Osimertinib in 1L EGFR-Mutant Advanced NSCLC: A Randomized, Double-Blind, Exploratory Analysis from MARIPOSA
    Lee, S. -H.
    Cho, B. C.
    Hayashi, H.
    Felip, E.
    Spira, A. I.
    Girard, N.
    Kim, Y. J.
    Ostapenko, Y.
    Danchaivijitr, P.
    Liu, B.
    Alip, A.
    Korbenfeld, E.
    Mourao Dias, J.
    Lee, K. H.
    Xiong, H.
    How, S. H.
    Cheng, Y.
    Chang, G. -C.
    Yang, J. C. -H.
    Besse, B.
    Thomas, M.
    Curtin, J. C.
    Zhang, J.
    Xie, J.
    Sun, T.
    Martinez, M.
    Sethi, S.
    Knoblauch, R. E.
    Fennema, E.
    Daksh, M.
    Ennis, M.
    Bauml, J. M.
    Lu, S.
    JOURNAL OF THORACIC ONCOLOGY, 2024, 19 (10) : S12 - S12
  • [38] MARIPOSA: Randomized Phase 3 Study of First-line Amivantamab plus Lazertinib vs Osimertinib vs Lazertinib in EGFR-mutant NSCLC
    Shreeve, S. M.
    Martinez, M.
    Verheijen, R. B.
    Xie, J.
    Sun, T.
    Haddish-Berhane, N.
    Curtin, J. C.
    Karkera, J.
    Pang, D.
    Roshak, A.
    Knoblauch, R. E.
    Patel, K.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (03) : S620 - S621
  • [39] The Usefulness of Liquid Biopsy for ctDNA in Patients with EGFR-Mutant NSCLC During and After Treatment with EGFR-TKIs
    Yokoyama, T.
    Naka, G.
    Ishida, H.
    Kishi, K.
    Ohashi, Y.
    Kunitoh, H.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S2223 - S2223
  • [40] Neoadjuvant EGFR-TKI Therapy for EGFR-Mutant NSCLC: A Systematic Review and Pooled Analysis of Five Prospective Clinical Trials
    Sun, Li
    Guo, Yi-Jia
    Song, Jun
    Wang, Yan-Ru
    Zhang, Shu-Ling
    Huang, Le-Tian
    Zhao, Jian-Zhu
    Jing, Wei
    Han, Cheng-Bo
    Ma, Jie-Tao
    FRONTIERS IN ONCOLOGY, 2021, 10