Red-shifted two-photon-sensitive phenanthridine photocages: synthesis and characterisation

被引:0
|
作者
Attiach, Celest M. [1 ]
Kumar, Amit [1 ]
Daniel, Jonathan [2 ]
Blanchard-Desce, Mireille [2 ]
Maruani, Antoine [1 ]
Dalko, Peter I. [1 ]
机构
[1] Univ Paris Cite, Lab Chim & Biochim Pharmacol & Toxicol, CNRS, F-75006 Paris, France
[2] Univ Bordeaux, CNRS, ISM, Bordeaux INP,UMR 5255, F-33400 Talence, France
关键词
PHOTOREMOVABLE PROTECTING GROUPS; 2-PHOTON; SENSITIVITY; ABSORPTION;
D O I
10.1039/d4cc02852j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Herein we describe the rational design, synthesis and photophysical study of a novel class of phenanthridine-based, one- and two-photon sensitive, photoremovable protecting groups with absorption wavelengths extending beyond 400 nm. This design facilitated the development of scaffolds with enhanced uncaging quantum yield, paving the way for broader applications in controlled drug delivery and molecular manipulation. A novel class of phenanthridine-based, one- and two-photon sensitive, photoremovable protecting groups with absorption wavelengths extending beyond 400 nm.
引用
收藏
页码:8260 / 8263
页数:4
相关论文
共 50 条
  • [31] Synthesis of tetraphenyltetraacenaphthoporphyrin: A new highly conjugated porphyrin system with remarkably red-shifted electronic absorption spectra
    Lash, TD
    Chandrasekar, P
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (36) : 8767 - 8768
  • [32] Synthesis of Red-Shifted 8-Hydroxyquinoline Derivatives Using Click Chemistry and Their Incorporation into Phosphorylation Chemosensors
    Gonzalez-Vera, Juan A.
    Lukovic, Elvedin
    Imperiali, Barbara
    JOURNAL OF ORGANIC CHEMISTRY, 2009, 74 (19): : 7309 - 7314
  • [34] o-Nitrobenzyl photolabile protecting groups with red-shifted absorption:: Syntheses and uncaging cross-sections for one- and two-photon excitation
    Aujard, Isabelle
    Benbrahim, Chouaha
    Gouget, Marine
    Ruel, Odile
    Baudin, Jean-Bernard
    Neveu, Pierre
    Jullien, Ludovic
    CHEMISTRY-A EUROPEAN JOURNAL, 2006, 12 (26) : 6865 - 6879
  • [35] Large red-shifted NIR absorption in azulenyl- and iodinated-modified BODIPYs sensitive to aggregation and protonation stimuli
    Zhao, Chunrui
    Wu, Bin
    Yang, Jufang
    Baryshnikov, Glib, V
    Zhou, Yunyun
    Agren, Hans
    Zou, Qi
    Zhu, Liangliang
    DYES AND PIGMENTS, 2022, 197
  • [36] Sensitive Detection of p65 Homodimers Using Red-Shifted and Fluorescent Protein-Based FRET Couples
    Goedhart, Joachim
    Vermeer, Joop E. M.
    Adjobo-Hermans, Merel J. W.
    van Weeren, Laura
    Gadella, Theodorus W. J., Jr.
    PLOS ONE, 2007, 2 (10):
  • [37] Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery
    Yang, Yang
    Yang, YanFang
    Xie, XiangYang
    Wang, ZhiYuan
    Gong, Wei
    Zhang, Hui
    Li, Ying
    Yu, FangLin
    Li, ZhiPing
    Mei, XingGuo
    BIOMATERIALS, 2015, 48 : 84 - 96
  • [38] Enhanced red-shifted radiation by pulse trapping in photonic crystal fibers with two zero-dispersion wavelengths
    Cheng, Chunfu
    Wang, Youqing
    Ou, Yiwen
    Lv, Qinghua
    OPTICS AND LASER TECHNOLOGY, 2012, 44 (04): : 954 - 959
  • [39] Synthesis and luminescence properties of new red-shifted absorption lanthanide(III) chelates suitable for peptide and protein labelling
    Maindron, Nicolas
    Poupart, Severine
    Hamon, Maxime
    Langlois, Jean-Baptiste
    Ple, Nelly
    Jean, Ludovic
    Romieu, Anthony
    Renard, Pierre-Yves
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 9 (07) : 2357 - 2370
  • [40] TP-2Rho Is a Sensitive Solvatochromic Red-Shifted Probe for Monitoring the Interactions between CDK4 and CyclinD
    Pellerano, Morgan
    Naud-Martin, Delphine
    Peyressatre, Marion
    Prevel, Camille
    Teulade-Fichou, Marie-Paule
    Morris, May
    Mahuteau-Betzer, Florence
    CHEMBIOCHEM, 2016, 17 (08) : 737 - 744