Red-shifted two-photon-sensitive phenanthridine photocages: synthesis and characterisation

被引:0
|
作者
Attiach, Celest M. [1 ]
Kumar, Amit [1 ]
Daniel, Jonathan [2 ]
Blanchard-Desce, Mireille [2 ]
Maruani, Antoine [1 ]
Dalko, Peter I. [1 ]
机构
[1] Univ Paris Cite, Lab Chim & Biochim Pharmacol & Toxicol, CNRS, F-75006 Paris, France
[2] Univ Bordeaux, CNRS, ISM, Bordeaux INP,UMR 5255, F-33400 Talence, France
关键词
PHOTOREMOVABLE PROTECTING GROUPS; 2-PHOTON; SENSITIVITY; ABSORPTION;
D O I
10.1039/d4cc02852j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Herein we describe the rational design, synthesis and photophysical study of a novel class of phenanthridine-based, one- and two-photon sensitive, photoremovable protecting groups with absorption wavelengths extending beyond 400 nm. This design facilitated the development of scaffolds with enhanced uncaging quantum yield, paving the way for broader applications in controlled drug delivery and molecular manipulation. A novel class of phenanthridine-based, one- and two-photon sensitive, photoremovable protecting groups with absorption wavelengths extending beyond 400 nm.
引用
收藏
页码:8260 / 8263
页数:4
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