Effect of 12-week high-intensity interval training on hemodynamic variables at rest and during exercise in patients with obstructive sleep apnoea

This study aimed to investigate the impact of 12 weeks of high-intensity interval training (HIIT) on hemodynamic variables at rest and during exercise in patients with obstructive sleep apnoea. Twenty-six obese adults with moderate-to-severe OSA (AHI = 42 +/- 22.9 e/h) were randomly assigned to HIIT or a control group. Sleep parameters, ambulatorial, aortic, and during-exercise SBP and DBP were assessed at baseline and after 12 weeks. Generalized estimated equations assessed differences between groups over time. When compared with control group, HIIT reduced AHI (17.1 +/- 6.2; e/h, P < 0.01), SBPnighttime (10.2 +/- 5.0 mmHg; P = 0.034), DBPnighttime (7.9 +/- 4.0 mmHg; P = 0.038), DBPaortic (5.5 +/- 2.9 mmHg; P = 0.048), and SBPmax (29.6 +/- 11.8 mmHg; P = 0.045). In patients with OSA, 12 weeks of HIIT decreases sleep apnoea severity and blood pressure in rest and during exercise.