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Univ Vita Salute San Raffaele, IRCCS San Raffaele Sci Inst, Div Gastroenterol & Gastrointestinal Endoscopy, Dept Expt Oncol, Via Olgettina 60, I-20136 Milan, Italy Univ Vita Salute San Raffaele, IRCCS San Raffaele Sci Inst, Div Gastroenterol & Gastrointestinal Endoscopy, Dept Expt Oncol, Via Olgettina 60, I-20136 Milan, Italy