Deoxygenative cross-coupling of aryl ketones with (Hetero)arenes mediated by a TiCl4/Ammonia borane system

被引：0
|
作者：
Zang, Yong-jun [1 ]
Zhou, Shi-jie [1 ]
Qian, Chen [1 ]
Xu, Qi-lin [1 ]
Li, Guo-si [1 ]
Li, Xing [2 ]
Zhu, Fu-cheng [1 ]
机构：
[1] West Anhui Univ, Dept Biol & Pharmaceut Engn, Anhui Prov Key Lab Qual Evaluat & Improvement Trad, Luan 237012, Anhui, Peoples R China
[2] Taizhou Univ, Lege Pharm & Chem & Chem Engn, Taizhou 225300, Jiangsu, Peoples R China
来源：
TETRAHEDRON | 2024年 / 163卷
基金：
中国国家自然科学基金;
关键词：
Deoxygenative coupling; Aromatic ketones; Ammonia borane; Titanium tetrachloride; FRIEDEL-CRAFTS ALKYLATION; REDUCTIVE ALKYLATION; ARENES; TRIARYLMETHANES; INDOLES;
D O I：
10.1016/j.tet.2024.134147
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and mild protocol for the direct deoxygenative coupling of aryl ketones with electron-rich (hetero) arenes to construct the C(sp2)- 2 )- C(sp3) 3 ) bond was achieved, which was mediated by TiCl4 4 and by using ammonia borane (AB) as the reductant. This strategy provides a novel protocol for the synthesis of unsymmetrical diaryland triarylmethanes.
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页数：6
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