Deep Brain Stimulation Mechanisms in Parkinson's Disease: Immediate and Long-Term Effects

被引：2
|
作者：
Pei, Honglong [1 ]
Wu, Zhenghan [1 ]
Ma, Li [1 ]
Wang, Jun [1 ]
Li, Jinghui [1 ]
Geng, Xin [1 ]
Zou, Yanghong [1 ]
Zhang, Mou [1 ]
Qi, Renli [1 ]
Yu, Hualin [1 ]
机构：
[1] Kunming Med Univ, Affiliated Hosp 1, Dept Neurosurg 2, Kunming 650101, Yunnan, Peoples R China
来源：
JOURNAL OF INTEGRATIVE NEUROSCIENCE | 2024年 / 23卷 / 06期
关键词：
basal ganglia; beta oscillations; deep brain stimulation; neuroprotection; neurotransmitters; Parkinson's disease; HIGH-FREQUENCY STIMULATION; SUBTHALAMIC NUCLEUS STIMULATION; STRIATAL DOPAMINE RELEASE; GLOBUS-PALLIDUS INTERNA; BASAL GANGLIA; ALPHA-SYNUCLEIN; ELECTRICAL-STIMULATION; PEDUNCULOPONTINE NUCLEUS; NEUROTROPHIC FACTOR; BETA OSCILLATIONS;
D O I：
10.31083/j.jin2306114
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Deep brain stimulation (DBS) is a common therapy for managing Parkinson's disease (PD) in clinical practice. However, a complete understanding of its mode of action is still needed. DBS is believed to work primarily through electrical and neurochemical pathways. Furthermore, DBS has other mechanisms of action. This review explores the fundamental concepts and applications of DBS in treating PD, including its mechanisms, clinical implications, and recent research.
引用
收藏
页数：18
相关论文
共 50 条
  • [21] Long-term safety and efficacy of frameless subthalamic deep brain stimulation in Parkinson’s disease
    Danilo Genovese
    Francesco Bove
    Leonardo Rigon
    Tommaso Tufo
    Alessandro Izzo
    Paolo Calabresi
    Anna Rita Bentivoglio
    Carla Piano
    Neurological Sciences, 2024, 45 : 565 - 572
  • [22] Long-Term Analysis of Deep Brain Stimulation in Parkinson's Disease: Beyond 5 Years
    Knight-Greenfield, Ashley
    Cheung, Tyler
    Raciti, Loredana
    Alterman, Ron L.
    Tagliati, Michele
    NEUROLOGY, 2011, 76 (09) : A277 - A277
  • [23] Long-term follow up of unilateral deep brain stimulation for Parkinson's disease (PD)
    Sarmento, F.
    Daga, A.
    Wang, A.
    de Araujo, T.
    Aghili-Mehrizi, S.
    Wong, J. K.
    MOVEMENT DISORDERS, 2024, 39 : S543 - S543
  • [24] Long-term cognitive outcome of bilateral subthalamic deep brain stimulation in Parkinson's disease
    Kim, H. -J.
    Jeon, B. S.
    Kim, J. -Y.
    Kim, H. J.
    Shin, C. -W.
    MOVEMENT DISORDERS, 2014, 29 : S348 - S349
  • [25] Long-term outcomes of subthalamic nucleus deep brain stimulation for Parkinson's disease in Singapore
    Cai, Yi Zhan
    Zheng, Yilong
    Li, Wei
    Ehsan, Saffari Seyed
    Ng, Hwee Lan
    Zhan, Angela
    Xu, Zheyu
    Tay, Kay Yaw
    Au, Wing Lok
    Ng, Wai Hoe
    Tan, Louis Chew Seng
    Rui, Wan Kai
    Neo, Shermyn
    ANNALS ACADEMY OF MEDICINE SINGAPORE, 2024, 53 (08) : 481 - 489
  • [26] Long-term cognitive outcome of bilateral subthalamic deep brain stimulation in Parkinson’s disease
    Han-Joon Kim
    Beom S. Jeon
    Sun Ha Paek
    Kyoung-Min Lee
    Ji-Young Kim
    Jee-Young Lee
    Hee Jin Kim
    Ji Young Yun
    Young Eun Kim
    Hui-Jun Yang
    Gwanhee Ehm
    Journal of Neurology, 2014, 261 : 1090 - 1096
  • [27] Deep brain stimulation in Parkinson's disease: A multicentric, long-term, observational pilot study
    Scelzo, Emma
    Beghi, Ettore
    Rosa, Manuela
    Angrisano, Serena
    Antonini, Angelo
    Bagella, Caterina
    Bianchi, Elisa
    Caputo, Elena
    Lena, Francesco
    Lopiano, Leonardo
    Marcante, Andrea
    Marceglia, Sara
    Massaro, Francesco
    Modugno, Nicola
    Pacchetti, Claudio
    Pilleri, Manuela
    Pozzi, Nicolo Gabriele
    Romito, Luigi Michele
    Sandlli, Marco
    Tamma, Filippo
    Weis, Luca
    Zibetti, Maurizio
    Priori, Alberto
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2019, 405
  • [28] Long-term cognitive outcome of bilateral subthalamic deep brain stimulation in Parkinson's disease
    Kim, Han-Joon
    Jeon, Beom S.
    Paek, Sun Ha
    Lee, Kyoung-Min
    Kim, Ji-Young
    Lee, Jee-Young
    Kim, Hee Jin
    Yun, Ji Young
    Kim, Young Eun
    Yang, Hui-Jun
    Ehm, Gwanhee
    JOURNAL OF NEUROLOGY, 2014, 261 (06) : 1090 - 1096
  • [29] Focal Subthalamic Atrophy After Long-Term Deep Brain Stimulation in Parkinson's Disease
    Gelpi, Ellen
    Haberler, Christine
    Micko, Alexander
    Polt, Andrea
    Amon, Andreas
    Rossler, Karl
    Alesch, Francois
    MOVEMENT DISORDERS, 2021, 36 (08) : 1987 - 1989
  • [30] Long-term safety and efficacy of frameless subthalamic deep brain stimulation in Parkinson's disease
    Genovese, Danilo
    Bove, Francesco
    Rigon, Leonardo
    Tufo, Tommaso
    Izzo, Alessandro
    Calabresi, Paolo
    Bentivoglio, Anna Rita
    Piano, Carla
    NEUROLOGICAL SCIENCES, 2024, 45 (02) : 565 - 572
12345