Pd-Catalyzed Hydroboration of Vinylarenes with B2pin2

被引：0

作者：

Wan, Yunhui ^{[1
]}

Lu, Yingpeng ^{[2
]}

Ren, Yi ^{[1
,2
]}

Xu, Hongxi ^{[1
]}

Zhao, Gang ^{[2
]}

Zheng, Changwu ^{[1
,2
]}

机构：

[1] Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Lab Fluorine & Nitrogen Chem & Adv Mat, Shanghai 200032, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 12期

基金：

上海市自然科学基金;

关键词：

MARKOVNIKOV-SELECTIVE HYDROBORATION; CROSS-COUPLING REACTIONS; ALKENES; ESTERS;

D O I：

10.1021/acs.joc.4c00431

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium(II)-catalyzed Markovnikov hydroboration of aryl alkenes with readily available bis(pinacolato)diboron (B(2)pin(2)) is reported. The reaction proceeded with low catalyst loading (0.5 mol %) in the absence of N- or P-containing ligands, affording the products in up to 90% yield. Trifluoracetic acid serves as the hydrogen source, enabling the synthesis of benzylic boronic esters under mild ambient conditions.

引用

页码：9056 / 9062

页数：7

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