Visual and portable detection of metronidazole realized by metal-organic framework flexible sensor and smartphone scanning

Metronidazole （MNZ） is a type of antibiotic that can help people and animals cure bacterial in fections,however,abuse of MNZ has posed a threat to human health.Hence,portable and vi sual detection of MNZ is meaningful for food safety and rational administration of drugs,bu full of challenges.Hence,a porous three-dimensional Tb-based metal-organic framework (MOF{（CH3）2NH2·[Tb5（TDA）8（H2O）2]·6DMF·2C2H5OH}_n（TDA-Tb） with good solvent and p H stabilities was pre pared,and the framework possesses one-dimensional channels with a diameter of 12 A along the c-axis Experiment results suggest that the synthesized TDA-Tb can selectively and sensitively detect MNZ in water,and the limit of detection （LOD） is as low as 4.1×10-7mol/L.Moreover,a flexible sensor TDA Tb-M was also constructed by incorporating TDA-Tb into membrane materials for convenient usage.And the TDA-Tb-M firstly realized portable and visual detection of MNZ through smartphone scanning,which may inspire more probes with wide application ranges.