In this paper, we prove a local H¨older estimate of(K1, K2)-quasiconformal mappings between n-dimensional hypersurfaces of Rn+1under an assumption of bounded mean curvature of the original hypersurface M. With some new ingredients of the isoperimetric inequality and the co-area formula on manifolds, we extend Simon's work of quasiconformal mappings on surfaces of R3 to the setting of n-dimensional hypersurfaces of Rn+1.