Neuroendocrine differentiation in prostate cancer

被引：0
|
作者：
Jingwen WangYang Yao Department of OncologyShanghai Sixth Peoples HospitalJiaotong UniversityShanghai China [200233 ]
机构：
来源：
Chinese-German Journal of Clinical Oncology | 2008年 / 03期
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中图分类号：
R737.25 [前列腺肿瘤];
学科分类号：
摘要：
Hormonal therapy is an important treatment for advanced/metastatic prostate cancer. But it can induce neuroen-docrine(NE) differentiation in prostate cancer cells. These NE cells will secrete manifold neural peptide or hormones which can lead to androgen-independent growth of non-NE tumor cells. When this happens,hormonal therapy becomes useless and indicates bad prognosis. In this paper,the mechanism of neuroendocrine differentiation and its relationship with andro-gen-independent were reviewed.
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页码：150 / 153
页数：4
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