The role of reactive oxygen species in gastric cancer

被引：0

作者：

Yuqi Wang ^{[1
,2
,3
,4
]}

Jingli Xu ^{[2
,3
,4
]}

Zhenjie Fu ^{[2
,3
,4
]}

Ruolan Zhang ^{[2
,3
,4
]}

Weiwei Zhu ^{[2
,3
,4
]}

Qianyu Zhao ^{[2
,3
,4
]}

Ping Wang ^{[1
]}

Can Hu ^{[2
,3
,4
]}

Xiangdong Cheng ^{[2
,3
,4
]}

机构：

[1] College of Pharmaceutical Sciences, Zhejiang University of Technology

[2] Department of Gastric Surgery, Zhejiang Cancer Hospital

[3] Key Laboratory of Prevention

[4] Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer, Zhejiang Cancer

来源：

Cancer Biology & Medicine | 2024年 / 21卷 / 09期

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Gastric cancer(GC) ranks fifth in cancer incidence and fourth in cancer-related mortality worldwide. Reactive oxygen species(ROS) are highly oxidative oxygen-derived products that have crucial roles in cell signaling regulation and maintaining internal balance. ROS are closely associated with the occurrence, development, and treatment of GC. This review summarizes recent findings on the sources of ROS and the bidirectional regulatory effects on GC and discusses various treatment modalities for GC that are related to ROS induction. In addition, the regulation of ROS by natural small molecule compounds with the highest potential for development and applications in anti-GC research is summarized. The aim of the review is to accelerate the clinical application of modulating ROS levels as a therapeutic strategy for GC.

引用

页码：740 / 753

页数：14

共 50 条

[21] THE ROLE OF REACTIVE OXYGEN SPECIES IN ONCOGENESIS
Wong, E.
Hayes, P.
Knaus, U. G.
IRISH JOURNAL OF MEDICAL SCIENCE, 2011, 180 : S520 - S520
[22] Role of reactive oxygen species in the microcirculation
Kavdia, Mahendra
FASEB JOURNAL, 2007, 21 (06): : A848 - A848
[23] The role of reactive oxygen species in atherosclerosis
Mügge, A
ZEITSCHRIFT FUR KARDIOLOGIE, 1998, 87 (11): : 851 - 864
[24] The Role of Reactive Oxygen Species in Atherogenesis
Lichtenberg, Dov
Pinchuk, Ilya
FREE RADICAL BIOLOGY AND MEDICINE, 2012, 53 : S168 - S168
[25] Role of reactive oxygen species in glomerulonephritis
Gwinner, W
Gröne, HJ
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2000, 15 (08) : 1127 - 1132
[26] The differential role of reactive oxygen species in early and late stages of cancer
Assi, Mohamad
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2017, 313 (06) : R646 - R653
[27] Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species
Kusmartsev, S
Gabrilovich, DI
JOURNAL OF LEUKOCYTE BIOLOGY, 2003, 74 (02) : 186 - 196
[28] Role of Reactive Oxygen Species in Estrogen Dependant Breast Cancer Complication
Johar, Ramesh
Sharma, Rohit
Kaur, Amanpreet
Mukherjee, Tapan K.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2016, 16 (02) : 190 - 199
[29] The role of nitric oxide, reactive nitrogen and oxygen species in lung cancer
Bencova, Alica
Antosova, Martina
Mokra, Daniela
Kocan, Ivan
Rozborilova, Eva
EUROPEAN RESPIRATORY JOURNAL, 2015, 46
[30] Reactive oxygen species and colorectal cancer
Lin, Sisi
Li, Yongyu
Zamyatnin, Andrey A., Jr.
Werner, Jens
Bazhin, Alexandr V.
JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 233 (07) : 5119 - 5132

← 1 2 3 4 5 →