Early detection of pancreatic cancer in the era of precision medicine

被引:0
|
作者
Ahmed, Taha M. [1 ]
Kawamoto, Satomi [1 ]
Lopez-Ramirez, Felipe [1 ]
Yasrab, Mohammad [1 ]
Hruban, Ralph H. [2 ]
Fishman, Elliot K. [1 ]
Chu, Linda C. [1 ]
机构
[1] Johns Hopkins Univ Hosp, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ, Sol Goldman Pancreat Canc Res Ctr, Dept Pathol, Sch Med, Baltimore, MD USA
关键词
Pancreatic ductal adenocarcinoma; Cancer screening; CT; MRI; Artificial intelligence; Liquid biopsy; CIRCULATING TUMOR-CELLS; METHYLATION-BASED BIOMARKERS; DUCTAL ADENOCARCINOMA; HIGH-RISK; DNA; DIAGNOSIS; CT; PROGRESSION; SIGNATURE; EXOSOMES;
D O I
10.1007/s00261-024-04358-w
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality and it is often diagnosed at advanced stages due to non-specific clinical presentation. Disease detection at localized disease stage followed by surgical resection remains the only potentially curative treatment. In this era of precision medicine, a multifaceted approach to early detection of PDAC includes targeted screening in high-risk populations, serum biomarkers and "liquid biopsies", and artificial intelligence augmented tumor detection from radiologic examinations. In this review, we will review these emerging techniques in the early detection of PDAC.
引用
收藏
页码:3559 / 3573
页数:15
相关论文
共 50 条
  • [11] Gastric Cancer in the Era of Precision Medicine
    Liu, Xi
    Meltzer, Stephen J.
    CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2017, 3 (03): : 348 - 358
  • [12] Cancer Evolution in Precision Medicine Era
    Karagiannis, Dimitris
    Rampias, Theodoros
    CANCERS, 2022, 14 (08)
  • [13] Colorectal cancer in the era of precision medicine
    Borg, Christophe
    BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2023, 207 (09): : 1229 - 1233
  • [14] Breast cancer in the era of precision medicine
    Sarhangi, Negar
    Hajjari, Shahrzad
    Heydari, Seyede Fatemeh
    Ganjizadeh, Maryam
    Rouhollah, Fatemeh
    Hasanzad, Mandana
    MOLECULAR BIOLOGY REPORTS, 2022, 49 (10) : 10023 - 10037
  • [15] Lung Cancer in the Era of Precision Medicine
    Politi, Katerina
    Herbst, Roy S.
    CLINICAL CANCER RESEARCH, 2015, 21 (10) : 2213 - 2220
  • [16] Breast cancer in the era of precision medicine
    Negar Sarhangi
    Shahrzad Hajjari
    Seyede Fatemeh Heydari
    Maryam Ganjizadeh
    Fatemeh Rouhollah
    Mandana Hasanzad
    Molecular Biology Reports, 2022, 49 : 10023 - 10037
  • [17] Early Returns From the Era of Precision Medicine
    Cutler, David M.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (02): : 109 - 110
  • [18] Integrative cancer genomics in the era of precision cancer medicine
    Johji Inazawa
    Yoshio Miki
    Yusuke Nakamura
    Journal of Human Genetics, 2021, 66 : 843 - 843
  • [19] Integrative cancer genomics in the era of precision cancer medicine
    Inazawa, Johji
    Miki, Yoshio
    Nakamura, Yusuke
    JOURNAL OF HUMAN GENETICS, 2021, 66 (09) : 843 - 843
  • [20] Breast cancer screening in the precision medicine era
    Thompson, C. K.
    Fiscalini, A. S.
    Donnellan, P.
    Kaplan, C. P.
    Madlensky, L.
    Eklund, M.
    Ziv, E.
    van't Veer, L. J.
    Tice, J. A.
    Esserman, L. J.
    CANCER RESEARCH, 2016, 76