Tardive Dysphoria With Selective-Serotonin Reuptake Inhibitors Treated Successfully With Atypical Antidepressants: A Case Series From Tertiary Hospital Setting

被引：0
|
作者：
Bhattacharjee, Debanjan [1 ]
Mahto, Sumit Kumar [2 ]
Prithviraj, H. K. Tejaswi [3 ]
Poornima, H. K. Surakshitha [4 ]
机构：
[1] Cent Hosp Dhori, Psychiat, Phusro, India
[2] All India Inst Med Sci, Pharmacol, Deogarh, India
[3] Adichunchanagiri Inst Med Sci, Psychiat, Mandya, India
[4] Hosp & Res Inst, Sri Chamundeshwari Med Coll, Psychiat, Channapatna, India
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 03期
关键词：
treatment-resistant depression; selective serotonin reuptake inhibitors; antidepressant; mood disorders; tardive dysphoria;
D O I：
10.7759/cureus.56684
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Tardive dysphoria (TDp) is a phenomenon characterized by the delayed onset or worsening of depressive symptoms following the discontinuation or alteration of antidepressant medications. TDp is a recently defined, under-recognized, and understudied condition. We present a series of five TDp cases exploring the diverse presentations, management strategies, and associated medical conditions. In all the cases, TDp manifested after prolonged use of selective serotonin reuptake inhibitors (SSRIs). All cases were successfully managed with atypical antidepressants. These cases offer insight into TDp, providing clinicians and researchers with examples of atypical trajectories in depressive symptomatology.
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