Neural and Neural Crest-Derived Stem Cell Distribution in the Adult Human Dental Pulp

被引:0
|
作者
Alzer, Heba [1 ]
Abu Shahin, Nisreen [2 ]
Alsoleihat, Firas [1 ,3 ]
机构
[1] Univ Jordan, Sch Dent, Dept Restorat Dent, Amman 11942, Jordan
[2] Univ Jordan, Sch Med, Dept Pathol Microbiol & Forens Med, Amman 11942, Jordan
[3] Univ Petra, Fac Dent, Dept Restorat Dent & Basic Med Sci, Amman 11196, Jordan
来源
INTERNATIONAL JOURNAL OF MORPHOLOGY | 2024年 / 42卷 / 02期
关键词
NCAM1; Nestin; SNAIL/SLUG; SOX9; S100; Human dental pulp; Stem cells; Neural stem cells; Neural crest; SIDE POPULATION CELLS; IN-VITRO; TOOTH;
D O I
暂无
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Despite comprehensive studies and reports about the properties of dental pulp stem cells (DPSCs) in vitro, we still need to confirm whether these in vitro characteristics coincide with the nature of DPSCs in situ. The anatomical location of DPSCs populations in the dental pulp has yet to be investigated. Moreover, the mesenchymal DPSCs have been much more studied than the neural crest -derived DPSCs. In this study, well -recognized neural/neural crest stem cell markers NCAM1, Nestin, SNAIL/SLUG, SOX9, and S100 are being investigated by immunohistochemistry to localize the precise location of these populations of DPSCs within the human adult dental pulp. All previously mentioned markers were expressed in the dental pulp, and their intensity and location of expression were reported.
引用
收藏
页码:510 / 515
页数:6
相关论文
共 50 条
  • [31] Heterogeneity of neural crest-derived melanocytes
    Cichorek, Miroslawa
    Wachulska, Malgorzata
    Stasiewicz, Aneta
    CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 2013, 8 (04): : 315 - 330
  • [32] Neural crest-derived horizontal basal cells as tissue stem cells in the adult olfactory epithelium
    Suzuki, Jun
    Yoshizaki, Kaichi
    Kobayashi, Toshimitsu
    Osumi, Noriko
    NEUROSCIENCE RESEARCH, 2013, 75 (02) : 112 - 120
  • [33] CHARACTERISATION OF HUMAN GINGIVAL NEURAL CREST-DERIVED STEM CELLS IN MONOLAYER AND NEUROSPHERE CULTURES
    Fournier, B. P.
    Loison-Robert, L. S.
    Ferre, F. C.
    Owen, G. R.
    Larjava, H.
    Hakkinen, L.
    EUROPEAN CELLS & MATERIALS, 2016, 31 : 40 - 58
  • [34] Neuronal regeneration in injured rat spinal cord after human dental pulp derived neural crest stem cell transplantation
    Kabatas, S.
    Demir, C. S.
    Civelek, E.
    Yilmaz, I
    Kircelli, A.
    Yilmaz, C.
    Akyuva, Y.
    Karaoz, E.
    BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, 2018, 119 (03): : 143 - 151
  • [35] Isolation and Characterization of Neural Crest-Derived Stem Cells From Adult Ovine Palatal Tissue
    Zeuner, Marie-Theres
    Didenko, Nikolai N.
    Humphries, David
    Stergiadis, Sokratis
    Morash, Taryn M.
    Pater, Ketan
    Grimm, Wolf-Dieter
    Widera, Darius
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2018, 6
  • [36] Development of the neural crest-derived intrinsic innervation of the human lung
    Burns, Alan J.
    Thapar, Nikhil
    Barlow, Amanda J.
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2008, 38 (03) : 269 - 275
  • [37] Transcriptome Analysis Reveals High Similarities between Adult Human Cardiac Stem Cells and Neural Crest-Derived Stem Cells
    Hoeving, Anna L.
    Sielemann, Katharina
    Greiner, Johannes F. W.
    Kaltschmidt, Barbara
    Knabbe, Cornelius
    Kaltschmidt, Christian
    BIOLOGY-BASEL, 2020, 9 (12): : 1 - 22
  • [38] Osteogenic differentiation of human dental neural crest-derived progenitor cells:: a model for developing bone
    Degistirici, O.
    Grabellus, F.
    Irsen, S.
    Schmid, K. W.
    Thie, M.
    TISSUE ENGINEERING PART A, 2008, 14 (05) : 766 - 766
  • [39] Induction of neural crest cells from human dental pulp-derived induced pluripotent stem cells
    Kawano, Eisuke
    Toriumi, Taku
    Iguchi, Shinya
    Suzuki, Daigo
    Sato, Shuichi
    Honda, Masaki
    BIOMEDICAL RESEARCH-TOKYO, 2017, 38 (02): : 135 - 147
  • [40] Neural crest-derived multipotent cells in the adult mouse iris stroma
    Kikuchi, Miki
    Hayashi, Ryuhei
    Kanakubo, Sachiko
    Ogasawara, Ayumi
    Yamato, Masayuki
    Osumi, Noriko
    Nishida, Kohji
    GENES TO CELLS, 2011, 16 (03) : 273 - 281