Liver kinase B1 (LKB1) staves off γδ T-cell-mediated autoimmune liver disease

被引：0
|
作者：
Wang, Yiwen [1 ]
Wu, Lan [1 ]
Van Kaer, Luc [1 ]
机构：
[1] Vanderbilt Univ, Sch Med, Dept Pathol Microbiol & Immunol, Nashville, TN 37212 USA
来源：
CELLULAR & MOLECULAR IMMUNOLOGY | 2024年 / 21卷 / 06期
关键词：
D O I：
10.1038/s41423-024-01172-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：641 / 642
页数：2
相关论文
共 50 条
  • [31] Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects
    Swisa, Avital
    Granot, Zvi
    Tamarina, Natalia
    Sayers, Sophie
    Bardeesy, Nabeel
    Philipson, Louis
    Hodson, David J.
    Wikstrom, Jakob D.
    Rutter, Guy A.
    Leibowitz, Gil
    Glaser, Benjamin
    Dor, Yuval
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (34) : 20934 - 20946
  • [32] Autophagy inhibition sensitizes liver kinase b1 (LKB1)-deficient kras-driven lung tumors to MEK inhibitor trametinib.
    Bhatt, Vrushank Dharmesh
    Lan, Taijin
    Wang, Wenping
    Khayati, Khoosheh
    Cararo-Lopes, Eduardo
    Wang, Jianming
    Kong, Jerry
    Raju, Akash
    Luo, Xuefei
    Hu, Wenwei
    Su, Xiaoyang
    White, Eileen
    Guo, Jessie Yanxiang
    CANCER RESEARCH, 2021, 81 (13)
  • [33] The Liver Kinase B1 Is a Central Regulator of T Cell Development, Activation, and Metabolism
    MacIver, Nancie J.
    Blagih, Julianna
    Saucillo, Donte C.
    Tonelli, Luciana
    Griss, Takla
    Rathmell, Jeffrey C.
    Jones, Russell G.
    JOURNAL OF IMMUNOLOGY, 2011, 187 (08): : 4187 - 4198
  • [34] LIVER KINASE B1 AS AN ONCOGENIC DRIVER IN LIVER CANCER
    Garcia-Rodriguez, J. L.
    Zubiete-Franco, I.
    Fernandez-Ramos, D.
    Fernandez-Tussy, P.
    Barbier-Torres, L.
    Lopitz-Otsoa, F.
    Gutierrez-de Juan, V.
    Martin-Plagaro, C.
    Aspichueta, P.
    Boix, L.
    Bruix, J.
    Calvisi, D. F.
    Varela-Rey, M.
    Fraga, M. F.
    Beraza, N.
    Lu, S. C.
    Mato, J. M.
    Delgado, T. C.
    Martinez-Chantar, M. L.
    JOURNAL OF HEPATOLOGY, 2015, 62 : S403 - S403
  • [35] The LKB1 tumor suppressor kinase in human disease
    Katajisto, Pekka
    Vallenius, Tea
    Vaahtomeri, Kari
    Ekman, Niklas
    Udd, Lina
    Tiainen, Marianne
    Makela, Tomi P.
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2007, 1775 (01): : 63 - 75
  • [36] Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge
    Miller, Edward J.
    Calamaras, Timothy
    Elezaby, Aly
    Sverdlov, Aaron
    Qin, Fuzhong
    Luptak, Ivan
    Wang, Ke
    Sun, Xinxin
    Vijay, Andrea
    Croteau, Dominique
    Bachschmid, Markus
    Cohen, Richard A.
    Walsh, Kenneth
    Colucci, Wilson S.
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2016, 5 (01):
  • [37] Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease
    Skog, Oskar
    Korsgren, Stella
    Melhus, Asa
    Korsgren, Olle
    CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY, 2013, 20 (02) : 118 - 123
  • [38] SUMOYLATION CONTROLS THE LOCALIZATION AND ACTIVITY OF LKB1 IN LIVER CANCER
    Zubiete-Franco, I.
    Lopitz-Otsoa, F.
    Fernandez-Tussy, P.
    Delgado, T.
    Martinez-Chantar, M.
    JOURNAL OF HEPATOLOGY, 2016, 64 : S565 - S566
  • [39] Liver kinase B1 (LKB1) reduced inflammation and oxidative stress by regulating the AMPK/NLRP3 signaling pathway in LPS-induced lung injury
    Yifeng Yue
    Liwu Zong
    Yongmin Chen
    Nianhai Feng
    Junxia Tang
    Hongyu Xu
    Meiling Zhao
    Molecular & Cellular Toxicology, 2021, 17 : 385 - 395
  • [40] Loss of liver kinase B1 in human seminoma
    Kumar, Manish
    Sahoo, Subhransu S. S.
    Jamaluddin, M. Fairuz B.
    Tanwar, Pradeep S. S.
    FRONTIERS IN ONCOLOGY, 2023, 13
12345