VasCog Screen test: sensitive in detecting cognitive impairment in patients who had a stroke or with heart failure

被引:1
|
作者
Chen, Nicole Yun Ching [1 ]
Tan, Melissa Yi Ling [2 ]
Xu, Jing [3 ]
Zuo, Lijun [4 ]
Dong, Yanhong [5 ]
机构
[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore
[2] Natl Univ Singapore, Dept Med, Singapore, Singapore
[3] Duke NUS Med Sch, Ctr Quantitat Med, Singapore, Singapore
[4] Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China
[5] Natl Univ Singapore, Alice Lee Ctr Nursing Studies, Yong Loo Lin Sch Med, Beijing, Singapore
基金
英国医学研究理事会;
关键词
Stroke; Cerebrovascular Disorders; Cognitive Dysfunction; Brain; MINI-MENTAL-STATE; CANADIAN STROKE; NEUROLOGICAL DISORDERS; NATIONAL INSTITUTE; ISCHEMIC-STROKE; MOCA; MMSE; VALIDATION; VALIDITY; SCALE;
D O I
10.1136/svn-2023-002701
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction Vascular diseases, such as stroke and heart failure (HF), are associated with cognitive decline. Vascular cognitive impairment (CI) is commonly found in patients who had a stroke and with HF, ranging from mild CI to dementia. Early detection of CI is crucial for effective management and rehabilitation. This study aimed to develop the VasCog Screen test, a screening tool to detect CI in patients who had a stroke and with HF.Method 427 patients who had a stroke and with HF were assessed using cognitive measures including Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) and a formal neuropsychological battery. The short-MoCA was derived and combined with Symbol Digit Modalities Test (SDMT) to create the VasCog Screen. The discriminatory ability of different tests for CI was compared, establishing optimal cut-off points. Variants of short-MoCA including the SDMT were also evaluated.Results Similar prevalence rates of CI were found in stroke and HF cohorts. The most prevalent neuropsychological impairment was visuomotor speed, followed by visual memory and visuoconstruction. More than half of the patients were found to have CI. The VasCog Screen outperformed MMSE, MoCA and short-MoCA in detecting CI. The addition of SDMT to variants of the short-MoCA increased diagnostic accuracy.Conclusion The VasCog Screen test offers a cognitive screening tool, which is sensitive to cognitive deficits characteristically found in patients who had a stroke and with HF. It was found to have good sensitivity, specificity and classification accuracy. It is easy to administer in busy clinics, enabling early detection of CI and facilitating appropriate interventions.
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页数:7
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