Recent progress and prospects in the organocatalytic Morita-Baylis-Hillman reaction

被引：2
|
作者：
Maneesha, Mohammed [1 ]
Haritha, S. H. [2 ]
Aneeja, Thaipparambil [1 ]
Anilkumar, Gopinathan [1 ,3 ]
机构：
[1] Mahatma Gandhi Univ, Sch Chem Sci, Priyadarsini Hills P O, Kottayam 686560, Kerala, India
[2] Sree Narayana Coll, Postgrad Dept Chem, Thiruvananthapuram 695145, Kerala, India
[3] Mahatma Gandhi Univ, Inst Integrated Programmes & Res Basic Sci IIRBS, Priyadarsini Hills P O, Kottayam 686560, Kerala, India
来源：
RSC ADVANCES | 2024年 / 14卷 / 21期
关键词：
Carbon - Rate constants - Unsaturated compounds;
D O I：
10.1039/d4ra02369b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The organocatalytic asymmetric Morita-Baylis-Hillman (MBH) reaction produces a significant carbon-carbon bond formation that involves the addition of alpha,beta-unsaturated carbonyl compounds to activated alkenes to give alpha-methylene-beta-hydroxycarbonyl compounds. Commercially available starting materials, excellent atom economy, mild reaction conditions, and flexible products are the major highlights of this method. In this review, we discuss the recent developments in the organocatalytic MBH reaction, covering literature from 2018 to 2023. The organocatalytic Morita-Baylis-Hillman (MBH) reaction, one of the most significant carbon-carbon bond formations involves the addition of alpha,beta-unsaturated carbonyl compounds to activated alkenes to give alpha-methylene-beta-hydroxycarbonyl compounds.
引用
收藏
页码：14949 / 14963
页数：15
相关论文
共 50 条
  • [21] Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates
    Jing Peng
    HaiLei Cui
    YingChun Chen
    Science China Chemistry, 2011, 54 : 81 - 86
  • [22] Organocatalytic enantioselective methodologies using Morita-Baylis-Hillman carbonates and acetates
    Rios, Ramon
    CATALYSIS SCIENCE & TECHNOLOGY, 2012, 2 (02) : 267 - 278
  • [23] Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates
    Peng Jing
    Cui HaiLei
    Chen YingChun
    SCIENCE CHINA-CHEMISTRY, 2011, 54 (01) : 81 - 86
  • [24] Organocatalytic asymmetric allylic amination of Morita-Baylis-Hillman carbonates of isatins
    Zhang, Hang
    Zhang, Shan-Jun
    Zhou, Qing-Qing
    Dong, Lin
    Chen, Ying-Chun
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2012, 8 : 1241 - 1245
  • [25] Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates
    PENG JingCUI HaiLei CHEN YingChun Key Laboratory of DrugTargeting and Drug Delivery SystemMinistry of Education
    Department of Medicinal ChemistryWest China School of PharmacySichuan UniversityChengdu China
    Science China(Chemistry), 2011, 54 (01) : 81 - 86
  • [26] Organocatalytic asymmetric allylic alkylation of oxindoles with Morita-Baylis-Hillman carbonates
    Jiang, Kun
    Peng, Jing
    Cui, Hai-Lei
    Chen, Ying-Chun
    CHEMICAL COMMUNICATIONS, 2009, (26) : 3955 - 3957
  • [27] Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates
    PENG Jing
    Department of Medicinal Chemistry
    Science China(Chemistry), 2011, (01) : 81 - 86
  • [28] Toward the development of an asymmetric Morita-Baylis-Hillman reaction
    Lin, YM
    Boucau, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U3441 - U3441
  • [29] Ionic Thiourea Organocatalysis of the Morita-Baylis-Hillman Reaction
    McGrath, Trevor
    Robertson, Katherine N.
    Masuda, Jason D.
    Clyburne, Jason A. C.
    Singer, Robert D.
    AUSTRALIAN JOURNAL OF CHEMISTRY, 2016, 69 (07) : 759 - 762
  • [30] Catalytic Enantioselective Transannular Morita-Baylis-Hillman Reaction
    Mato, Raquel
    Manzano, Ruben
    Reyes, Efraim
    Carrillo, Luisa
    Uria, Uxue
    Vicario, Jose L.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (24) : 9495 - 9499
12345