Recent progress and prospects in the organocatalytic Morita-Baylis-Hillman reaction

被引：2

作者：

Maneesha, Mohammed ^{[1
]}

Haritha, S. H. ^{[2
]}

Aneeja, Thaipparambil ^{[1
]}

Anilkumar, Gopinathan ^{[1
,3
]}

机构：

[1] Mahatma Gandhi Univ, Sch Chem Sci, Priyadarsini Hills P O, Kottayam 686560, Kerala, India

[2] Sree Narayana Coll, Postgrad Dept Chem, Thiruvananthapuram 695145, Kerala, India

[3] Mahatma Gandhi Univ, Inst Integrated Programmes & Res Basic Sci IIRBS, Priyadarsini Hills P O, Kottayam 686560, Kerala, India

来源：

RSC ADVANCES | 2024年 / 14卷 / 21期

关键词：

Carbon - Rate constants - Unsaturated compounds;

D O I：

10.1039/d4ra02369b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The organocatalytic asymmetric Morita-Baylis-Hillman (MBH) reaction produces a significant carbon-carbon bond formation that involves the addition of alpha,beta-unsaturated carbonyl compounds to activated alkenes to give alpha-methylene-beta-hydroxycarbonyl compounds. Commercially available starting materials, excellent atom economy, mild reaction conditions, and flexible products are the major highlights of this method. In this review, we discuss the recent developments in the organocatalytic MBH reaction, covering literature from 2018 to 2023. The organocatalytic Morita-Baylis-Hillman (MBH) reaction, one of the most significant carbon-carbon bond formations involves the addition of alpha,beta-unsaturated carbonyl compounds to activated alkenes to give alpha-methylene-beta-hydroxycarbonyl compounds.

引用

页码：14949 / 14963

页数：15

共 50 条

[1] Recent developments in the asymmetric organocatalytic Morita-Baylis-Hillman reaction
Pellissier, Helene
TETRAHEDRON, 2017, 73 (20) : 2831 - 2861
[2] Asymmetric organocatalytic Morita-Baylis-Hillman reaction and asymmetric organocatalytic transformations of Morita-Baylis-Hillman adducts. An update
Pellissier, Helene
TETRAHEDRON, 2025, 172
[3] Recent progress in the Morita-Baylis-Hillman reactions
Iwabuchi, Y
Hatakeyama, S
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2002, 60 (01) : 2 - 14
[4] Recent Advances in Organocatalytic Asymmetric Morita-Baylis-Hillman/aza-Morita-Baylis-Hillman Reactions
Wei, Yin
Shi, Min
CHEMICAL REVIEWS, 2013, 113 (08) : 6659 - 6690
[5] Recent extensions of the Morita-Baylis-Hillman reaction
Ma, Guang-Ning
Jiang, Jia-Jun
Shi, Min
Wei, Yin
CHEMICAL COMMUNICATIONS, 2009, (37) : 5496 - 5514
[6] Organocatalytic Enantioselective Morita-Baylis-Hillman Reaction of Maleimides with Isatins
Chauhan, Pankaj
Chimni, Swapandeep Singh
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2 (07) : 586 - 592
[7] An unexpected organocatalytic asymmetric tandem Michael/Morita-Baylis-Hillman reaction
Cabrera, Silvia
Aleman, Jose
Bolze, Patrick
Bertelsen, Soren
Jorgensen, Karl Anker
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (01) : 121 - 125
[8] Organocatalytic Asymmetric Morita-Baylis-Hillman Reaction of Isatins with Vinyl Sulfones
He, Hong-Jiao
Wang, Rui-Qi
Wan, Lin-Xi
Zhou, Li-Yan
Li, Hong-Yan
Li, Guo-Bo
Xiao, You-Cai
Chen, Fen -Er
JOURNAL OF ORGANIC CHEMISTRY, 2023, 88 (06): : 3802 - 3807
[9] Enantioselective, Organocatalytic Morita-Baylis-Hillman and Aza-Morita-Baylis-Hillman Reactions: Stereochemical Issues
Mansilla, Javier
Saa, Jose M.
MOLECULES, 2010, 15 (02): : 709 - 734
[10] Organocatalytic Allylic Amination of Morita-Baylis-Hillman Carbonates
Formanek, Bedrich
Simek, Michal
Kamlar, Martin
Cisarova, Ivana
Vesely, Jan
SYNTHESIS-STUTTGART, 2019, 51 (04): : 907 - 920

← 1 2 3 4 5 →