Thalidomide for Bleeding from Small-Intestinal Angiodysplasia

被引：1

作者：

Topa, Matilde ^{[1
]}

Pessarelli, Tommaso ^{[1
]}

Elli, Luca ^{[2
]}

Sey, Michael ^{[3
]}

Hsia, Cyrus ^{[3
]}

Jairath, Vipul ^{[3
]}

Chen, Huimin ^{[4
]}

Wu, Shan ^{[5
]}

Ge, Zhizheng ^{[6
]}

机构：

[1] Univ Milan, Milan, Italy

[2] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy

[3] Western Univ, London, ON, Canada

[4] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Shanghai, Peoples R China

[5] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 6, Sch Med, Shanghai, Peoples R China

[6] Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Shanghai, Peoples R China

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2024年 / 390卷 / 05期

关键词：

MANAGEMENT; DIAGNOSIS;

D O I：

10.1056/NEJMc2314599

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To the Editor: Chen et al. (Nov. 2 issue)(1) found a significant decrease in recurrent suspected small-bowel bleeding due to small-intestinal angiodysplasia (SIA) among thalidomide-treated patients, as well as reasonable short-term safety with respect to thalidomide therapy. However, the article lacks crucial specifics. The enrolled patients needed to have SIA and be unsuitable candidates for endoscopic treatment, yet relevant details about the clinical features of the lesions or the demographic characteristics of the patients that justified the exclusion of enteroscopic treatment are omitted. Moreover, the exclusion criteria regarding clinically relevant coexisting conditions and the median age of the patients (<65 . . .

引用

页码：471 / 475

页数：5

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