Current state of signaling pathways associated with the pathogenesis of idiopathic pulmonary fibrosis

被引:0
|
作者
Zhou, Yang [1 ]
Ling, Tingting [1 ]
Shi, Weihong [1 ]
机构
[1] Jiangsu Vocat Coll Med, Sch Med, Yancheng 224005, Jiangsu, Peoples R China
关键词
Idiopathic pulmonary fibrosis; Signaling pathways; Review; LUNG FIBROSIS; GROWTH-FACTOR; INHIBITION; CELLS; DIFFERENTIATION; RECEPTOR; MODEL; BETA; MICE; TRANSITION;
D O I
10.1186/s12931-024-02878-z
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Idiopathic Pulmonary Fibrosis (IPF) represents a chronic and progressive pulmonary disorder distinguished by a notable mortality rate. Despite the elusive nature of the pathogenic mechanisms, several signaling pathways have been elucidated for their pivotal roles in the progression of this ailment. This manuscript aims to comprehensively review the existing literature on the signaling pathways linked to the pathogenesis of IPF, both within national and international contexts. The objective is to enhance the comprehension of the pathogenic mechanisms underlying IPF and offer a scholarly foundation for the advancement of more efficacious therapeutic strategies, thereby fostering research and clinical practices within this domain.
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页数:8
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