Epidemiology and prevention of oropharyngeal cancer Summary of the new German S3 guideline

被引:0
|
作者
Dietz, Andreas [1 ]
机构
[1] Univ Leipzig, Klin & Poliklin Hals Nasen Ohrenheilkunde, Univ Klinikum Leipzig, Liebigstr 10, D-04103 Leipzig, Germany
来源
ONKOLOGIE | 2024年 / 30卷 / 07期
关键词
Oropharyngeal cancer/screening; Human papillomavirus 16; p16; expression; Human papillomavirus/vaccination; Human papillomavirus/screening; SQUAMOUS-CELL CARCINOMA; HPV-ASSOCIATED HEAD; HUMAN-PAPILLOMAVIRUS; ORAL-CAVITY; TONSILLAR CARCINOMAS; NECK-CANCER; RISK; P16; EXPRESSION; DNA;
D O I
10.1007/s00761-024-01540-z
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Due to the association with the causal human papillomavirus 16 (HPV16) infection, oropharyngeal squamous cell carcinoma is now separated into two distinct entities depending on HPV16 positivity. More recent data show a diversified picture of the importance and prevalence of the surrogate parameter p16 (discordance) for a definitive HPV16 association, which varies worldwide. In the context of preventive options, vaccination is of major importance and HPV screening of healthy people of less importance. The current CME article excerpts parts of the new German S3 guideline on diagnosis, treatment, prevention, and aftercare of oro- and hypopharyngeal cancer (version 1.0, March 2024; Association of the Scientific Medical Societies in Germany [AWMF] registration number 017-082OL).
引用
收藏
页码:631 / 642
页数:12
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